Chronic Dietary Supplementation of 4% Figs on the Modification of Oxidative Stress in Alzheimer’s Disease Transgenic Mouse Model

We assessed the changes in the plasma Aβ, oxidative stress/antioxidants, and membrane bound enzymes in the cerebral cortex and hippocampus of Alzheimer’s disease (AD) transgenic mice (Tg2576) after dietary supplementation of Omani figs fruits for 15 months along with spatial memory and learning test...

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Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-8
Hauptverfasser:	Subash, Selvaraju, Essa, Musthafa Mohamed, al-Asmi, Abdullah, al-Adawi, Samir, Vaishnav, Ragini
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase - metabolism Alzheimer Disease - blood Alzheimer Disease - pathology Alzheimer Disease - physiopathology Alzheimer's disease Amyloid beta-Peptides - blood Animal cognition Animals Antioxidants Antioxidants - metabolism Behavior Brain research Catalase - metabolism Cell Membrane - enzymology Cerebral Cortex - enzymology Cerebral Cortex - pathology Cerebral Cortex - physiopathology Diet therapy Dietary Supplements Disease Models, Animal Female Ficus - chemistry Free radicals Fruits Hippocampus - enzymology Hippocampus - pathology Hippocampus - physiopathology Humans Lipid Peroxidation Lipids Mice, Transgenic Nutrition research Oxidative Stress Pathogenesis Polyphenols Protein Carbonylation Proteins Rodents Spatial Memory Studies Superoxide Dismutase - metabolism
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