Synergistic acceleration in the osteogenesis of human mesenchymal stem cells by graphene oxide-calcium phosphate nanocomposites

Nanocomposites consisting of oblong ultrathin plate shaped calcium phosphate nanoparticles and graphene oxide microflakes were synthesized and have demonstrated markedly synergistic effect in accelerating stem cell differentiation to osteoblasts.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2014-08, Vol.50 (62), p.8484-8487
Hauptverfasser:	Tatavarty, Rameshwar, Ding, Hao, Lu, Guijin, Taylor, Robert J, Bi, Xiaohong
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical materials Calcium phosphate Calcium Phosphates - pharmacology Cell Differentiation - drug effects Graphene Graphite - pharmacology Human Humans Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - physiology Microscopy, Electron, Transmission Microscopy, Fluorescence Nanocomposites Nanocomposites - chemistry Nanocomposites - ultrastructure Nanoparticles Osteoblasts - cytology Osteogenesis - physiology Oxides Regenerative Medicine - methods Stem cells
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Beschreibung
Zusammenfassung:	Nanocomposites consisting of oblong ultrathin plate shaped calcium phosphate nanoparticles and graphene oxide microflakes were synthesized and have demonstrated markedly synergistic effect in accelerating stem cell differentiation to osteoblasts.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c4cc02442g