CD84 is markedly up‐regulated in Kawasaki disease arteriopathy

Summary The major goals of Kawasaki disease (KD) therapy are to reduce inflammation and prevent thrombosis in the coronary arteries (CA), but some children do not respond to currently available non‐specific therapies. New treatments have been difficult to develop because the molecular pathogenesis i...

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Veröffentlicht in:	Clinical and experimental immunology 2014-07, Vol.177 (1), p.203-211
Hauptverfasser:	Reindel, R., Bischof, J., Kim, K.‐Y. A., Orenstein, J. M., Soares, M. B., Baker, S. C., Shulman, S. T., Perlman, E. J., Lingen, M. W., Pink, A. J., Trevenen, C., Rowley, A. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Antigens, CD - genetics Antigens, CD - metabolism Antigens, Nuclear - genetics Antigens, Nuclear - metabolism Blood Platelets - immunology CD84 Cell Growth Processes - genetics Cell Movement - genetics Cell Survival - genetics Chronic Disease coronary artery aneurysm Coronary Vessels - pathology Female High-Throughput Screening Assays Humans Infant inflammation Kawasaki disease Male Mucocutaneous Lymph Node Syndrome - blood Mucocutaneous Lymph Node Syndrome - genetics Mucocutaneous Lymph Node Syndrome - immunology Myxovirus Resistance Proteins - genetics Myxovirus Resistance Proteins - metabolism Original Platelet Aggregation - genetics RNA, Messenger - analysis Signaling Lymphocytic Activation Molecule Family Transcription Factors - genetics Transcription Factors - metabolism Up-Regulation Vascular Calcification - blood Vascular Calcification - genetics Vascular Calcification - immunology vasculitis
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