Microbial ‘old friends’, immunoregulation and socioeconomic status

Summary The immune system evolved to require input from at least three sources that we collectively term the ‘old friends’: (i) the commensal microbiotas transmitted by mothers and other family members; (ii) organisms from the natural environment that modulate and diversify the commensal microbiotas...

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Veröffentlicht in:	Clinical and experimental immunology 2014-07, Vol.177 (1), p.1-12
Hauptverfasser:	Rook, G. A. W., Raison, C. L., Lowry, C. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Evolution Environmental Exposure host–pathogen interactions Humans Immune system Immune System - microbiology Immunomodulation Infection - immunology Infection - microbiology Infections inflammation Life Style Medical research Microbiota - immunology regulatory T cells Review Socioeconomic Factors Urbanization
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