Dynamic expression of extracellular signal-regulated kinase in rat liver tissue during hepatic fibrogenesis

AIM： To investigate whether extracellular signal-regulated kinase 1 （ERK1） is activated and associated with hepatic stellate cell （HSC） proliferation in fibrotic rat liver tissue. METHODS： Rat hepatic fibrosis was induced by bile duct ligation （BDL）. Histopathological changes were evalo uated by her...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2006-10, Vol.12 (39), p.6376-6381
Hauptverfasser:	Zhang, Xiao-Lan, Liu, Jin-Ming, Yang, Chang-Chun, Zheng, Yi-Lin, Liu, Li, Wang, Zhan-Kui, Jiang, Hui-Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - genetics Actins - metabolism Animals Cell Proliferation Gene Expression Regulation, Enzymologic - genetics Hepatocytes - metabolism Hepatocytes - pathology Liver - enzymology Liver - metabolism Liver - pathology Liver Cirrhosis - enzymology Liver Cirrhosis - metabolism Liver Cirrhosis - pathology Male Mitogen-Activated Protein Kinase 3 - genetics Mitogen-Activated Protein Kinase 3 - metabolism Rapid Communication Rats Rats, Sprague-Dawley RNA, Messenger - genetics RNA, Messenger - metabolism 肝纤维肝组织
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