The timing of bowel preparation before colonoscopy determines the quality of cleansing, and is a significant factor contributing to the detection of flat lesions: A randomized study

AIM: To compare the cleansing quality of polyethylene glycol electrolyte solution and sodium phosphate with different schedules of administration, and to evaluate whether the timing of the administration of bowel preparation affects the detection of polyps. METHODS: One hundred and seventy-seven con...

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Veröffentlicht in:World journal of gastroenterology : WJG 2006-10, Vol.12 (38), p.6161-6166
1. Verfasser: Adolfo Parra-Blanco David Nicolas-Pérez Antonio Gimeno-Garcia Begona Grosso Alejandro Jiménez Juan Ortega Enrique Quintero
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container_title World journal of gastroenterology : WJG
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creator Adolfo Parra-Blanco David Nicolas-Pérez Antonio Gimeno-Garcia Begona Grosso Alejandro Jiménez Juan Ortega Enrique Quintero
description AIM: To compare the cleansing quality of polyethylene glycol electrolyte solution and sodium phosphate with different schedules of administration, and to evaluate whether the timing of the administration of bowel preparation affects the detection of polyps. METHODS: One hundred and seventy-seven consecutive outpatients scheduled for colonoscopy were randomized in one of four groups to receive polyethylene glycol electrolyte solution or oral sodium phosphate with two different timing schedules. Quality of cleansing, polyp detection, and tolerance were evaluated. RESULTS: Patients receiving polyethylene glycol or sodium phosphate on the same day as the colonoscopy, obtained good to excellent global cleansing scores more frequently than patients who received polyethylene glycol or sodium phosphate on the day prior to the procedure (P 〈 0.001). Flat lesions, but not fiat adenomas, were more frequent in patients prepared on the same day (P = 0.02). CONCLUSION: The quality of colonic cleansing and the detection of fiat lesions are significantly improved when the preparation is taken on the day of the colonoscopy.
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METHODS: One hundred and seventy-seven consecutive outpatients scheduled for colonoscopy were randomized in one of four groups to receive polyethylene glycol electrolyte solution or oral sodium phosphate with two different timing schedules. Quality of cleansing, polyp detection, and tolerance were evaluated. RESULTS: Patients receiving polyethylene glycol or sodium phosphate on the same day as the colonoscopy, obtained good to excellent global cleansing scores more frequently than patients who received polyethylene glycol or sodium phosphate on the day prior to the procedure (P 〈 0.001). Flat lesions, but not fiat adenomas, were more frequent in patients prepared on the same day (P = 0.02). CONCLUSION: The quality of colonic cleansing and the detection of fiat lesions are significantly improved when the preparation is taken on the day of the colonoscopy.</description><identifier>ISSN: 1007-9327</identifier><identifier>EISSN: 2219-2840</identifier><identifier>DOI: 10.3748/wjg.v12.i38.6161</identifier><identifier>PMID: 17036388</identifier><language>eng</language><publisher>United States: Department of Gastroenterology, Hospital Universitario de Canarias, La Laguna 38109, Santa Cruz de Tenerife, Spain%Research Unit, Hospital Universitario de Canarias, La Laguna 38109, Santa Cruz de Tenerife, Spain</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cathartics - administration &amp; dosage ; Cathartics - adverse effects ; Clinical Research ; Colonic Polyps - diagnosis ; Colonic Polyps - pathology ; Colonoscopy ; Female ; Humans ; Male ; Middle Aged ; Phosphates - administration &amp; dosage ; Phosphates - adverse effects ; Polyethylene Glycols - administration &amp; dosage ; Polyethylene Glycols - adverse effects ; Time Factors ; 消化疾病 ; 结肠镜检查 ; 聚乙烯</subject><ispartof>World journal of gastroenterology : WJG, 2006-10, Vol.12 (38), p.6161-6166</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><rights>2006 Baishideng Publishing Group Co., Limited. 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dosage</topic><topic>Cathartics - adverse effects</topic><topic>Clinical Research</topic><topic>Colonic Polyps - diagnosis</topic><topic>Colonic Polyps - pathology</topic><topic>Colonoscopy</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Phosphates - administration &amp; dosage</topic><topic>Phosphates - adverse effects</topic><topic>Polyethylene Glycols - administration &amp; dosage</topic><topic>Polyethylene Glycols - adverse effects</topic><topic>Time Factors</topic><topic>消化疾病</topic><topic>结肠镜检查</topic><topic>聚乙烯</topic><toplevel>online_resources</toplevel><creatorcontrib>Adolfo Parra-Blanco David Nicolas-Pérez Antonio Gimeno-Garcia Begona Grosso Alejandro Jiménez Juan Ortega Enrique Quintero</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>World journal of gastroenterology : WJG</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Adolfo Parra-Blanco David Nicolas-Pérez Antonio Gimeno-Garcia Begona Grosso Alejandro Jiménez Juan Ortega Enrique Quintero</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The timing of bowel preparation before colonoscopy determines the quality of cleansing, and is a significant factor contributing to the detection of flat lesions: A randomized study</atitle><jtitle>World journal of gastroenterology : WJG</jtitle><addtitle>World Journal of Gastroenterology</addtitle><date>2006-10-14</date><risdate>2006</risdate><volume>12</volume><issue>38</issue><spage>6161</spage><epage>6166</epage><pages>6161-6166</pages><issn>1007-9327</issn><eissn>2219-2840</eissn><abstract>AIM: To compare the cleansing quality of polyethylene glycol electrolyte solution and sodium phosphate with different schedules of administration, and to evaluate whether the timing of the administration of bowel preparation affects the detection of polyps. 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identifier ISSN: 1007-9327
ispartof World journal of gastroenterology : WJG, 2006-10, Vol.12 (38), p.6161-6166
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source MEDLINE; PubMed Central; Alma/SFX Local Collection
subjects Adult
Aged
Aged, 80 and over
Cathartics - administration & dosage
Cathartics - adverse effects
Clinical Research
Colonic Polyps - diagnosis
Colonic Polyps - pathology
Colonoscopy
Female
Humans
Male
Middle Aged
Phosphates - administration & dosage
Phosphates - adverse effects
Polyethylene Glycols - administration & dosage
Polyethylene Glycols - adverse effects
Time Factors
消化疾病
结肠镜检查
聚乙烯
title The timing of bowel preparation before colonoscopy determines the quality of cleansing, and is a significant factor contributing to the detection of flat lesions: A randomized study
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