Synergistic effect of a novel oxymatrine-baicalin combination against hepatitis B virus replication, α smooth muscle actin expression and type I collagen synthesis in vitro

AIM： To study the effect of oxymatrine-baicalin combination （OB） against HBV replication in 2.2.15 cells and α smooth muscle actin （ α SMA） expression, type I, collagen synthesis in HSC-T6 cells. METHODS： The 2.2.15 cells and HSC-T6 cells were cultured and treated respectively. HBsAg and HBeAg in th...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2006-08, Vol.12 (32), p.5153-5159
Hauptverfasser:	Cheng, Yang, Ping, Jian, Xu, Huai-Dong, Fu, Hai-Jun, Zhou, Zhao-Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Alkaloids - administration & dosage Anti-Infective Agents - administration & dosage Antiviral Agents - administration & dosage Collagen Type I - biosynthesis Drug Synergism Drug Therapy, Combination Enzyme-Linked Immunosorbent Assay Flavonoids - administration & dosage Hepatitis B virus - drug effects Hepatitis B virus - metabolism Hepatitis B, Chronic - drug therapy Humans Liver - drug effects Liver - virology Quinolizines Viral Hepatitis 乙型病毒肝炎氧化苦参碱胶原质黄芩苷
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