Cationic Surface Charge Combined with Either Vitronectin or Laminin Dictates the Evolution of Human Embryonic Stem Cells/Microcarrier Aggregates and Cell Growth in Agitated Cultures

The expansion of human pluripotent stem cells (hPSC) for biomedical applications generally compels a defined, reliable, and scalable platform. Bioreactors offer a three-dimensional culture environment that relies on the implementation of microcarriers (MC), as supports for cell anchorage and their s...

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Veröffentlicht in:Stem cells and development 2014-07, Vol.23 (14), p.1688-1703
Hauptverfasser: Lam, Alan Tin-Lun, Li, Jian, Chen, Allen Kuan-Liang, Reuveny, Shaul, Oh, Steve Kah-Weng, Birch, William R.
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Sprache:eng
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