Carbapenemases in Gram-Negative Bacteria : Laboratory Detection and Clinical Significance
[...]simplex or multiplex PCR, real-time PCR, or hybridization tests could significantly improve detection of carbapenemase genes in clinical laboratory bypassing the sensitivity and specificity problems with phenotypic tests. [...]facing the global crisis in antibiotic resistance, presented by rapi...
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| Veröffentlicht in: | BioMed research international 2014-01, Vol.2014 (2014), p.1-3 |
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| container_title | BioMed research international |
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| creator | Bedenic, Branka Plecko, Vanda Sardelic, Sanda Uzunovic, Selma Torkar, Karmen Godic |
| description | [...]simplex or multiplex PCR, real-time PCR, or hybridization tests could significantly improve detection of carbapenemase genes in clinical laboratory bypassing the sensitivity and specificity problems with phenotypic tests. [...]facing the global crisis in antibiotic resistance, presented by rapid dissemination of carbapenemase producing Gram-negative bacteria, many issues remain controversial, especially detection methods and treatment options. |
| doi_str_mv | 10.1155/2014/841951 |
| format | Article |
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| source | MEDLINE; PubMed Central Open Access; Wiley-Blackwell Open Access Titles; PubMed Central; Alma/SFX Local Collection |
| subjects | Anti-Bacterial Agents - therapeutic use Antibiotics Bacteria Bacterial proteins Bacterial Proteins - genetics Bacterial Proteins - isolation & purification Bacteriology beta-Lactamases - genetics beta-Lactamases - isolation & purification Carbapenems Drug resistance in microorganisms Drug Resistance, Bacterial - genetics E coli Enzymes Genetic aspects Gram-negative bacteria Gram-Negative Bacteria - drug effects Gram-Negative Bacteria - enzymology Gram-Negative Bacteria - genetics Humans Infections Laboratories Microbiology Microorganisms Mortality Plasmids Properties Surveillance |
| title | Carbapenemases in Gram-Negative Bacteria : Laboratory Detection and Clinical Significance |
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