Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells

CCN family member 1 (CCN1), also known as cysteine-rich angiogenic inducer 61 (CYR61), belongs to the extracellular matrix-associated CCN protein family. The diverse functions of these proteins include regulation of cell migration, adhesion, proliferation, differentiation and survival/apoptosis, ind...

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Veröffentlicht in:	Cell communication and signaling 2014-06, Vol.12 (1), p.36-36, Article 36
Hauptverfasser:	Dotterweich, Julia, Ebert, Regina, Kraus, Sabrina, Tower, Robert J, Jakob, Franz, Schütze, Norbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiogenesis Apoptosis Bone diseases Bone marrow Cell growth Cell Line, Tumor Cells, Cultured Coculture Techniques Codon Colleges & universities Culture Media, Conditioned - pharmacology Cysteine Cysteine-Rich Protein 61 - genetics Cysteine-Rich Protein 61 - metabolism Cysteine-Rich Protein 61 - pharmacology Genetic transcription Hospitals Humans Insulin-like growth factors Integrins Interleukins Kinases Ligands Mesenchymal Stem Cells - metabolism Messenger RNA Mortality Multiple myeloma Multiple Myeloma - metabolism Osteoblasts - drug effects Osteoblasts - metabolism Physiological aspects Proteins Recombinant Proteins - pharmacology RNA Splicing RNA, Messenger - genetics RNA, Messenger - metabolism Stem cells Transcription, Genetic
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