Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung

Abstract We report a case of gefitinib-induced skin ulceration in a 50-year-old female with metastatic adenocarcinoma of lung who developed this adverse effect 2 weeks following initiation of gefitinib at a dose of 250 mg/day. The ulcer improved with stopping gefitinib for 2 weeks and also addition...

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Veröffentlicht in:Indian journal of medical and paediatric oncology 2014-01, Vol.35 (1), p.109-110
Hauptverfasser: Sathyanarayanan, Vishwanath, Lokesh, Kadabur Nagendrappa, Channaviriappa, Lakshmaiah Kuntejowdahalli, Jacob, Linu Abraham
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Sprache:eng
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Zusammenfassung:Abstract We report a case of gefitinib-induced skin ulceration in a 50-year-old female with metastatic adenocarcinoma of lung who developed this adverse effect 2 weeks following initiation of gefitinib at a dose of 250 mg/day. The ulcer improved with stopping gefitinib for 2 weeks and also addition of topical steroids and antibiotics. We are reporting this case to create awareness among treating oncologists of this adverse effect and also prompt interruption of therapy and topical steroids/antibiotics is useful to treat this adverse event.
ISSN:0971-5851
0975-2129
DOI:10.4103/0971-5851.133736