A secreted splice variant of the Xenopus frizzled-4 receptor is a biphasic modulator of Wnt signalling

Activation of the Wnt signalling cascade is primarily based on the interplay between Wnt ligands, their receptors and extracellular modulators. One prominent family of extracellular modulators is represented by the SFRP (secreted Frizzled-related protein) family. These proteins have significant simi...

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Veröffentlicht in:	Cell communication and signaling 2013-11, Vol.11 (1), p.89-89, Article 89
Hauptverfasser:	Gorny, Anne-Kathrin, Kaufmann, Lilian T, Swain, Rajeeb K, Steinbeisser, Herbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell interaction Cell receptors Embryo, Nonmammalian Embryonic Development - physiology Experiments Frizzled Receptors - physiology Genes Hybridization Ligands MAP Kinase Signaling System - physiology Physiological aspects Plasmids Protein Isoforms Proteins Short Report Wnt proteins Wnt Signaling Pathway - physiology Xenopus laevis Xenopus Proteins - physiology
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