NK cell-based immunotherapy for malignant diseases

Natural killer （NK） cells play critical roles in host immunity against cancer. In response, cancers develop mechanisms to escape NK cell attack or induce defective NK cells. Current NK cell-based cancer immunotherapy aims to overcome NK cell paralysis using several approaches. One approach uses expa...

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Veröffentlicht in:	Cellular & molecular immunology 2013-05, Vol.10 (3), p.230-252
Hauptverfasser:	Cheng, Min, Chen, Yongyan, Xiao, Weihua, Sun, Rui, Tian, Zhigang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive transfer Animals Antibodies Antigens Autoantigens Autografts Biomedical and Life Sciences Biomedicine Blood cells Cancer Cancer immunotherapy Cell Proliferation Cell therapy Clinical trials Clinical Trials as Topic Cord blood Fc receptors Good Manufacturing Practice Growth factors Histocompatibility Humans Immunity, Cellular - immunology Immunology Immunotherapy Inhibitory postsynaptic potentials Killer Cells, Natural - immunology Medical Microbiology Microbiology Natural killer cells Neoplasms - immunology Neoplasms - therapy NK细胞 Paralysis Pluripotency Quality control Review Stem cells Tumors Vaccine 免疫治疗免疫疗法基础多能干细胞恶性疾病自然杀伤细胞
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