Late-onset bloodstream infections of Very-Low-Birth-Weight infants: data from the Polish Neonatology Surveillance Network in 2009-2011
Late-Onset Bloodstream Infections (LO-BSI) continue to be one of the most important complications associated with hospitalization of infants born with very low birth weight (VLBW). The aims of this study were to assess the epidemiology of LO-BSI together with the risk factors and the distribution of...
Gespeichert in:
| Veröffentlicht in: | BMC infectious diseases 2014-06, Vol.14 (1), p.339-339, Article 339 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 339 |
|---|---|
| container_issue | 1 |
| container_start_page | 339 |
| container_title | BMC infectious diseases |
| container_volume | 14 |
| creator | Wójkowska-Mach, Jadwiga Gulczyńska, Ewa Nowiczewski, Marek Borszewska-Kornacka, Maria Domańska, Joanna Merritt, T Allen Helwich, Ewa Kordek, Agnieszka Pawlik, Dorota Gadzinowski, Janusz Szczapa, Jerzy Adamski, Paweł Sulik, Małgorzata Klamka, Jerzy Brzychczy-Włoch, Monika Heczko, Piotr B |
| description | Late-Onset Bloodstream Infections (LO-BSI) continue to be one of the most important complications associated with hospitalization of infants born with very low birth weight (VLBW). The aims of this study were to assess the epidemiology of LO-BSI together with the risk factors and the distribution of causative pathogens at six Polish neonatal intensive care units that participated in the Polish Neonatology Surveillance Network from January 1, 2009 to December 31, 2011.
The surveillance covered 1,695 infants whose birth weights were 72 hours after delivery. Case LO-BSI patients were defined according to NeoKISS.
Four hundred twenty seven episodes of LO-BSI were diagnosed with a frequency of 25.3% and an incidence density of 6.7/1000 patient-days (pds). Results of our multivariate analysis demonstrated that surgical procedures and lower gestational age were significantly associated with the risk of LO-BSI. Intravascular catheters were used in infants with LO-BSI significantly more frequently and/or for longer duration: Central venous cathters (CVC) (OR 1.29) and Peripheral venous catheters (PVC) (OR 2.8), as well as, the total duration of total parenteral nutrition (13 vs. 29 days; OR 1.81). Occurrence of LO-BSI was significantly associated with increased the length of mechanical ventilation (MV) (OR 2.65) or the continuous positive airway pressure (CPAP) (OR 2.51), as well as, the duration of antibiotic use (OR 2.98). The occurrence of more than one infection was observed frequently (OR 9.2) with VLBW with LO-BSI. Microorganisms isolated in infants with LO-BSI were dominated by Gram-positive cocci, and predominantly by coagulase-negative staphylococci (62.5%).
Independent risk factor for LO-BSI in VLBV infants are: low gestational age and requirement for surgery. The incidence rates of LO-BSI especially CVC-BSI were higher in the Polish NICUs surveillance than those of other national networks, similar to the central- and peripheral utilization ratio. |
| doi_str_mv | 10.1186/1471-2334-14-339 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4074408</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A539575275</galeid><sourcerecordid>A539575275</sourcerecordid><originalsourceid>FETCH-LOGICAL-b718t-1f01c76079339552025d46e9b923d638d6e706744d008c34e493cecae23176433</originalsourceid><addsrcrecordid>eNqNk01v1DAQhiMEoh9w54QscYGDi78SJxwqlVWBSiuKKJSj5XUmuy5JXGynZf8AvxtHW5YGFanywdbMM6_G79hZ9oySA0rL4jUVkmLGucBUYM6rB9nuNvTw1nkn2wvhghAqS1Y9znaYqHiVF3w3-zXXEbDrA0S0aJ2rQ_SgO2T7Bky0KYFcg87Br_HcXeO31scV_gZ2uYojo_sY3qBaR40a7zoUV4A-udaGFfoIrtfRtW65RmeDvwLbtro3kBLx2vnvqRwxQirMCKVPskeNbgM8vdn3s6_vjr_MPuD56fuT2dEcLyQtI6YNoUYWRFbpsnnOCMtrUUC1qBivC17WBUhSSCFqQkrDBaR7GjAaGKeyEJzvZ4cb3cth0UFtoI9et-rS2077tXLaqmmmtyu1dFdKkKRKyiQw2wgsrPuPwDRjXKfGOahxDumkUudJ5eVNG979GCBE1dlgYDQI3BAUzXNa0LIs-T1QkVzkLB9VX_yDXrjB98nPkaKskkyyv9RSt6DSDF3q04yi6ihPrsqcyTxRB3dQadXQWeN6aGyKTwpeTQoSE-FnXOohBHVy9vn-7On5lCUb1ngXgodm6zUlavwEd7n7_PaQtwV_Xj3_Df8V_ak</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1541297272</pqid></control><display><type>article</type><title>Late-onset bloodstream infections of Very-Low-Birth-Weight infants: data from the Polish Neonatology Surveillance Network in 2009-2011</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>Springer Nature OA Free Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>SpringerLink Journals - AutoHoldings</source><creator>Wójkowska-Mach, Jadwiga ; Gulczyńska, Ewa ; Nowiczewski, Marek ; Borszewska-Kornacka, Maria ; Domańska, Joanna ; Merritt, T Allen ; Helwich, Ewa ; Kordek, Agnieszka ; Pawlik, Dorota ; Gadzinowski, Janusz ; Szczapa, Jerzy ; Adamski, Paweł ; Sulik, Małgorzata ; Klamka, Jerzy ; Brzychczy-Włoch, Monika ; Heczko, Piotr B</creator><creatorcontrib>Wójkowska-Mach, Jadwiga ; Gulczyńska, Ewa ; Nowiczewski, Marek ; Borszewska-Kornacka, Maria ; Domańska, Joanna ; Merritt, T Allen ; Helwich, Ewa ; Kordek, Agnieszka ; Pawlik, Dorota ; Gadzinowski, Janusz ; Szczapa, Jerzy ; Adamski, Paweł ; Sulik, Małgorzata ; Klamka, Jerzy ; Brzychczy-Włoch, Monika ; Heczko, Piotr B</creatorcontrib><description>Late-Onset Bloodstream Infections (LO-BSI) continue to be one of the most important complications associated with hospitalization of infants born with very low birth weight (VLBW). The aims of this study were to assess the epidemiology of LO-BSI together with the risk factors and the distribution of causative pathogens at six Polish neonatal intensive care units that participated in the Polish Neonatology Surveillance Network from January 1, 2009 to December 31, 2011.
The surveillance covered 1,695 infants whose birth weights were <1501 grams (VLBW) in whom LO-BSI was diagnosed >72 hours after delivery. Case LO-BSI patients were defined according to NeoKISS.
Four hundred twenty seven episodes of LO-BSI were diagnosed with a frequency of 25.3% and an incidence density of 6.7/1000 patient-days (pds). Results of our multivariate analysis demonstrated that surgical procedures and lower gestational age were significantly associated with the risk of LO-BSI. Intravascular catheters were used in infants with LO-BSI significantly more frequently and/or for longer duration: Central venous cathters (CVC) (OR 1.29) and Peripheral venous catheters (PVC) (OR 2.8), as well as, the total duration of total parenteral nutrition (13 vs. 29 days; OR 1.81). Occurrence of LO-BSI was significantly associated with increased the length of mechanical ventilation (MV) (OR 2.65) or the continuous positive airway pressure (CPAP) (OR 2.51), as well as, the duration of antibiotic use (OR 2.98). The occurrence of more than one infection was observed frequently (OR 9.2) with VLBW with LO-BSI. Microorganisms isolated in infants with LO-BSI were dominated by Gram-positive cocci, and predominantly by coagulase-negative staphylococci (62.5%).
Independent risk factor for LO-BSI in VLBV infants are: low gestational age and requirement for surgery. The incidence rates of LO-BSI especially CVC-BSI were higher in the Polish NICUs surveillance than those of other national networks, similar to the central- and peripheral utilization ratio.</description><identifier>ISSN: 1471-2334</identifier><identifier>EISSN: 1471-2334</identifier><identifier>DOI: 10.1186/1471-2334-14-339</identifier><identifier>PMID: 24939563</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Analysis ; Bacteremia - blood ; Bacteremia - epidemiology ; Bacteremia - microbiology ; Bacteria - classification ; Bacteria - genetics ; Bacteria - isolation & purification ; Birth weight ; Cardiac arrhythmia ; Colleges & universities ; Cross Infection - blood ; Cross Infection - epidemiology ; Cross Infection - microbiology ; Diagnosis ; Epidemiological Monitoring ; Epidemiology ; Fatalities ; Female ; Health aspects ; Hospitalization ; Hospitals ; Humans ; Incidence ; Infant ; Infant, Newborn ; Infant, Very Low Birth Weight - blood ; Infections ; Intensive care ; Intensive Care Units, Neonatal - statistics & numerical data ; Male ; Mortality ; Neonatology ; Poland ; Risk Factors ; Sepsis ; Staphylococcal infections ; Statistical methods ; Surgery ; Variance analysis</subject><ispartof>BMC infectious diseases, 2014-06, Vol.14 (1), p.339-339, Article 339</ispartof><rights>COPYRIGHT 2014 BioMed Central Ltd.</rights><rights>2014 Wójkowska-Mach et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.</rights><rights>Copyright © 2014 Wójkowska-Mach et al.; licensee BioMed Central Ltd. 2014 Wójkowska-Mach et al.; licensee BioMed Central Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b718t-1f01c76079339552025d46e9b923d638d6e706744d008c34e493cecae23176433</citedby><cites>FETCH-LOGICAL-b718t-1f01c76079339552025d46e9b923d638d6e706744d008c34e493cecae23176433</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074408/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074408/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24939563$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wójkowska-Mach, Jadwiga</creatorcontrib><creatorcontrib>Gulczyńska, Ewa</creatorcontrib><creatorcontrib>Nowiczewski, Marek</creatorcontrib><creatorcontrib>Borszewska-Kornacka, Maria</creatorcontrib><creatorcontrib>Domańska, Joanna</creatorcontrib><creatorcontrib>Merritt, T Allen</creatorcontrib><creatorcontrib>Helwich, Ewa</creatorcontrib><creatorcontrib>Kordek, Agnieszka</creatorcontrib><creatorcontrib>Pawlik, Dorota</creatorcontrib><creatorcontrib>Gadzinowski, Janusz</creatorcontrib><creatorcontrib>Szczapa, Jerzy</creatorcontrib><creatorcontrib>Adamski, Paweł</creatorcontrib><creatorcontrib>Sulik, Małgorzata</creatorcontrib><creatorcontrib>Klamka, Jerzy</creatorcontrib><creatorcontrib>Brzychczy-Włoch, Monika</creatorcontrib><creatorcontrib>Heczko, Piotr B</creatorcontrib><title>Late-onset bloodstream infections of Very-Low-Birth-Weight infants: data from the Polish Neonatology Surveillance Network in 2009-2011</title><title>BMC infectious diseases</title><addtitle>BMC Infect Dis</addtitle><description>Late-Onset Bloodstream Infections (LO-BSI) continue to be one of the most important complications associated with hospitalization of infants born with very low birth weight (VLBW). The aims of this study were to assess the epidemiology of LO-BSI together with the risk factors and the distribution of causative pathogens at six Polish neonatal intensive care units that participated in the Polish Neonatology Surveillance Network from January 1, 2009 to December 31, 2011.
The surveillance covered 1,695 infants whose birth weights were <1501 grams (VLBW) in whom LO-BSI was diagnosed >72 hours after delivery. Case LO-BSI patients were defined according to NeoKISS.
Four hundred twenty seven episodes of LO-BSI were diagnosed with a frequency of 25.3% and an incidence density of 6.7/1000 patient-days (pds). Results of our multivariate analysis demonstrated that surgical procedures and lower gestational age were significantly associated with the risk of LO-BSI. Intravascular catheters were used in infants with LO-BSI significantly more frequently and/or for longer duration: Central venous cathters (CVC) (OR 1.29) and Peripheral venous catheters (PVC) (OR 2.8), as well as, the total duration of total parenteral nutrition (13 vs. 29 days; OR 1.81). Occurrence of LO-BSI was significantly associated with increased the length of mechanical ventilation (MV) (OR 2.65) or the continuous positive airway pressure (CPAP) (OR 2.51), as well as, the duration of antibiotic use (OR 2.98). The occurrence of more than one infection was observed frequently (OR 9.2) with VLBW with LO-BSI. Microorganisms isolated in infants with LO-BSI were dominated by Gram-positive cocci, and predominantly by coagulase-negative staphylococci (62.5%).
Independent risk factor for LO-BSI in VLBV infants are: low gestational age and requirement for surgery. The incidence rates of LO-BSI especially CVC-BSI were higher in the Polish NICUs surveillance than those of other national networks, similar to the central- and peripheral utilization ratio.</description><subject>Analysis</subject><subject>Bacteremia - blood</subject><subject>Bacteremia - epidemiology</subject><subject>Bacteremia - microbiology</subject><subject>Bacteria - classification</subject><subject>Bacteria - genetics</subject><subject>Bacteria - isolation & purification</subject><subject>Birth weight</subject><subject>Cardiac arrhythmia</subject><subject>Colleges & universities</subject><subject>Cross Infection - blood</subject><subject>Cross Infection - epidemiology</subject><subject>Cross Infection - microbiology</subject><subject>Diagnosis</subject><subject>Epidemiological Monitoring</subject><subject>Epidemiology</subject><subject>Fatalities</subject><subject>Female</subject><subject>Health aspects</subject><subject>Hospitalization</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infant, Very Low Birth Weight - blood</subject><subject>Infections</subject><subject>Intensive care</subject><subject>Intensive Care Units, Neonatal - statistics & numerical data</subject><subject>Male</subject><subject>Mortality</subject><subject>Neonatology</subject><subject>Poland</subject><subject>Risk Factors</subject><subject>Sepsis</subject><subject>Staphylococcal infections</subject><subject>Statistical methods</subject><subject>Surgery</subject><subject>Variance analysis</subject><issn>1471-2334</issn><issn>1471-2334</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNqNk01v1DAQhiMEoh9w54QscYGDi78SJxwqlVWBSiuKKJSj5XUmuy5JXGynZf8AvxtHW5YGFanywdbMM6_G79hZ9oySA0rL4jUVkmLGucBUYM6rB9nuNvTw1nkn2wvhghAqS1Y9znaYqHiVF3w3-zXXEbDrA0S0aJ2rQ_SgO2T7Bky0KYFcg87Br_HcXeO31scV_gZ2uYojo_sY3qBaR40a7zoUV4A-udaGFfoIrtfRtW65RmeDvwLbtro3kBLx2vnvqRwxQirMCKVPskeNbgM8vdn3s6_vjr_MPuD56fuT2dEcLyQtI6YNoUYWRFbpsnnOCMtrUUC1qBivC17WBUhSSCFqQkrDBaR7GjAaGKeyEJzvZ4cb3cth0UFtoI9et-rS2077tXLaqmmmtyu1dFdKkKRKyiQw2wgsrPuPwDRjXKfGOahxDumkUudJ5eVNG979GCBE1dlgYDQI3BAUzXNa0LIs-T1QkVzkLB9VX_yDXrjB98nPkaKskkyyv9RSt6DSDF3q04yi6ihPrsqcyTxRB3dQadXQWeN6aGyKTwpeTQoSE-FnXOohBHVy9vn-7On5lCUb1ngXgodm6zUlavwEd7n7_PaQtwV_Xj3_Df8V_ak</recordid><startdate>20140618</startdate><enddate>20140618</enddate><creator>Wójkowska-Mach, Jadwiga</creator><creator>Gulczyńska, Ewa</creator><creator>Nowiczewski, Marek</creator><creator>Borszewska-Kornacka, Maria</creator><creator>Domańska, Joanna</creator><creator>Merritt, T Allen</creator><creator>Helwich, Ewa</creator><creator>Kordek, Agnieszka</creator><creator>Pawlik, Dorota</creator><creator>Gadzinowski, Janusz</creator><creator>Szczapa, Jerzy</creator><creator>Adamski, Paweł</creator><creator>Sulik, Małgorzata</creator><creator>Klamka, Jerzy</creator><creator>Brzychczy-Włoch, Monika</creator><creator>Heczko, Piotr B</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QL</scope><scope>7T2</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>7U1</scope><scope>7U2</scope><scope>5PM</scope></search><sort><creationdate>20140618</creationdate><title>Late-onset bloodstream infections of Very-Low-Birth-Weight infants: data from the Polish Neonatology Surveillance Network in 2009-2011</title><author>Wójkowska-Mach, Jadwiga ; Gulczyńska, Ewa ; Nowiczewski, Marek ; Borszewska-Kornacka, Maria ; Domańska, Joanna ; Merritt, T Allen ; Helwich, Ewa ; Kordek, Agnieszka ; Pawlik, Dorota ; Gadzinowski, Janusz ; Szczapa, Jerzy ; Adamski, Paweł ; Sulik, Małgorzata ; Klamka, Jerzy ; Brzychczy-Włoch, Monika ; Heczko, Piotr B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b718t-1f01c76079339552025d46e9b923d638d6e706744d008c34e493cecae23176433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Analysis</topic><topic>Bacteremia - blood</topic><topic>Bacteremia - epidemiology</topic><topic>Bacteremia - microbiology</topic><topic>Bacteria - classification</topic><topic>Bacteria - genetics</topic><topic>Bacteria - isolation & purification</topic><topic>Birth weight</topic><topic>Cardiac arrhythmia</topic><topic>Colleges & universities</topic><topic>Cross Infection - blood</topic><topic>Cross Infection - epidemiology</topic><topic>Cross Infection - microbiology</topic><topic>Diagnosis</topic><topic>Epidemiological Monitoring</topic><topic>Epidemiology</topic><topic>Fatalities</topic><topic>Female</topic><topic>Health aspects</topic><topic>Hospitalization</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Incidence</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infant, Very Low Birth Weight - blood</topic><topic>Infections</topic><topic>Intensive care</topic><topic>Intensive Care Units, Neonatal - statistics & numerical data</topic><topic>Male</topic><topic>Mortality</topic><topic>Neonatology</topic><topic>Poland</topic><topic>Risk Factors</topic><topic>Sepsis</topic><topic>Staphylococcal infections</topic><topic>Statistical methods</topic><topic>Surgery</topic><topic>Variance analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wójkowska-Mach, Jadwiga</creatorcontrib><creatorcontrib>Gulczyńska, Ewa</creatorcontrib><creatorcontrib>Nowiczewski, Marek</creatorcontrib><creatorcontrib>Borszewska-Kornacka, Maria</creatorcontrib><creatorcontrib>Domańska, Joanna</creatorcontrib><creatorcontrib>Merritt, T Allen</creatorcontrib><creatorcontrib>Helwich, Ewa</creatorcontrib><creatorcontrib>Kordek, Agnieszka</creatorcontrib><creatorcontrib>Pawlik, Dorota</creatorcontrib><creatorcontrib>Gadzinowski, Janusz</creatorcontrib><creatorcontrib>Szczapa, Jerzy</creatorcontrib><creatorcontrib>Adamski, Paweł</creatorcontrib><creatorcontrib>Sulik, Małgorzata</creatorcontrib><creatorcontrib>Klamka, Jerzy</creatorcontrib><creatorcontrib>Brzychczy-Włoch, Monika</creatorcontrib><creatorcontrib>Heczko, Piotr B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMC infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wójkowska-Mach, Jadwiga</au><au>Gulczyńska, Ewa</au><au>Nowiczewski, Marek</au><au>Borszewska-Kornacka, Maria</au><au>Domańska, Joanna</au><au>Merritt, T Allen</au><au>Helwich, Ewa</au><au>Kordek, Agnieszka</au><au>Pawlik, Dorota</au><au>Gadzinowski, Janusz</au><au>Szczapa, Jerzy</au><au>Adamski, Paweł</au><au>Sulik, Małgorzata</au><au>Klamka, Jerzy</au><au>Brzychczy-Włoch, Monika</au><au>Heczko, Piotr B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Late-onset bloodstream infections of Very-Low-Birth-Weight infants: data from the Polish Neonatology Surveillance Network in 2009-2011</atitle><jtitle>BMC infectious diseases</jtitle><addtitle>BMC Infect Dis</addtitle><date>2014-06-18</date><risdate>2014</risdate><volume>14</volume><issue>1</issue><spage>339</spage><epage>339</epage><pages>339-339</pages><artnum>339</artnum><issn>1471-2334</issn><eissn>1471-2334</eissn><abstract>Late-Onset Bloodstream Infections (LO-BSI) continue to be one of the most important complications associated with hospitalization of infants born with very low birth weight (VLBW). The aims of this study were to assess the epidemiology of LO-BSI together with the risk factors and the distribution of causative pathogens at six Polish neonatal intensive care units that participated in the Polish Neonatology Surveillance Network from January 1, 2009 to December 31, 2011.
The surveillance covered 1,695 infants whose birth weights were <1501 grams (VLBW) in whom LO-BSI was diagnosed >72 hours after delivery. Case LO-BSI patients were defined according to NeoKISS.
Four hundred twenty seven episodes of LO-BSI were diagnosed with a frequency of 25.3% and an incidence density of 6.7/1000 patient-days (pds). Results of our multivariate analysis demonstrated that surgical procedures and lower gestational age were significantly associated with the risk of LO-BSI. Intravascular catheters were used in infants with LO-BSI significantly more frequently and/or for longer duration: Central venous cathters (CVC) (OR 1.29) and Peripheral venous catheters (PVC) (OR 2.8), as well as, the total duration of total parenteral nutrition (13 vs. 29 days; OR 1.81). Occurrence of LO-BSI was significantly associated with increased the length of mechanical ventilation (MV) (OR 2.65) or the continuous positive airway pressure (CPAP) (OR 2.51), as well as, the duration of antibiotic use (OR 2.98). The occurrence of more than one infection was observed frequently (OR 9.2) with VLBW with LO-BSI. Microorganisms isolated in infants with LO-BSI were dominated by Gram-positive cocci, and predominantly by coagulase-negative staphylococci (62.5%).
Independent risk factor for LO-BSI in VLBV infants are: low gestational age and requirement for surgery. The incidence rates of LO-BSI especially CVC-BSI were higher in the Polish NICUs surveillance than those of other national networks, similar to the central- and peripheral utilization ratio.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>24939563</pmid><doi>10.1186/1471-2334-14-339</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1471-2334 |
| ispartof | BMC infectious diseases, 2014-06, Vol.14 (1), p.339-339, Article 339 |
| issn | 1471-2334 1471-2334 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4074408 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central Open Access; Springer Nature OA Free Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; SpringerLink Journals - AutoHoldings |
| subjects | Analysis Bacteremia - blood Bacteremia - epidemiology Bacteremia - microbiology Bacteria - classification Bacteria - genetics Bacteria - isolation & purification Birth weight Cardiac arrhythmia Colleges & universities Cross Infection - blood Cross Infection - epidemiology Cross Infection - microbiology Diagnosis Epidemiological Monitoring Epidemiology Fatalities Female Health aspects Hospitalization Hospitals Humans Incidence Infant Infant, Newborn Infant, Very Low Birth Weight - blood Infections Intensive care Intensive Care Units, Neonatal - statistics & numerical data Male Mortality Neonatology Poland Risk Factors Sepsis Staphylococcal infections Statistical methods Surgery Variance analysis |
| title | Late-onset bloodstream infections of Very-Low-Birth-Weight infants: data from the Polish Neonatology Surveillance Network in 2009-2011 |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T20%3A52%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Late-onset%20bloodstream%20infections%20of%20Very-Low-Birth-Weight%20infants:%20data%20from%20the%20Polish%20Neonatology%20Surveillance%20Network%20in%202009-2011&rft.jtitle=BMC%20infectious%20diseases&rft.au=W%C3%B3jkowska-Mach,%20Jadwiga&rft.date=2014-06-18&rft.volume=14&rft.issue=1&rft.spage=339&rft.epage=339&rft.pages=339-339&rft.artnum=339&rft.issn=1471-2334&rft.eissn=1471-2334&rft_id=info:doi/10.1186/1471-2334-14-339&rft_dat=%3Cgale_pubme%3EA539575275%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1541297272&rft_id=info:pmid/24939563&rft_galeid=A539575275&rfr_iscdi=true |