How Fast is Your Camera? Timescales for Molecular Motion and their Role in Restraining Molecular Dynamics

High-resolution structural information is routinely available for soluble proteins, largely from x-ray crystallography and solution nuclear magnetic resonance (NMR). However, these techniques are far harder to apply to membrane-bound proteins; membrane proteins are generally reluctant to crystallize...

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Veröffentlicht in:	Biophysical journal 2014-06, Vol.106 (12), p.2549-2551
Hauptverfasser:	Romo, Tod D., Grossfield, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysics Calcium-Binding Proteins - chemistry Crystallography Lipid Bilayers - metabolism Magnetic Resonance Spectroscopy Membranes Molecular Dynamics Simulation Muscle Proteins - chemistry New and Notable NMR Nuclear magnetic resonance Proteins Proteolipids - chemistry Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism Solid solutions
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