Expression of LacdiNAc Groups on N-Glycans among Human Tumors Is Complex

Aberrant glycosylation of proteins and lipids is one of the characteristic features of malignantly transformed cells. The GalNAcβ1 → 4GlcNAc (LacdiNAc or LDN) group at the nonreducing termini of both N- and O-glycans is not generally found in mammalian cells. We previously showed that the expression...

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Veröffentlicht in:	BioMed research international 2014, Vol.2014 (2014), p.1-7
Hauptverfasser:	Hirano, Kiyoko, Matsuda, Akio, Shirai, Takashi, Furukawa, Kiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Bioengineering Biosynthesis Breast cancer Care and treatment Cell adhesion & migration Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology Colleges & universities Complications and side effects Development and progression Gene expression Glycoproteins Humans Influence Lactose - analogs & derivatives Lactose - metabolism Neoplasms - metabolism Neoplasms - pathology Pancreatic cancer Polysaccharides - metabolism Prostate cancer Review Rodents Tumors
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