Apical Abscission Alters Cell Polarity and Dismantles the Primary Cilium During Neurogenesis

Withdrawal of differentiating cells from proliferative tissue is critical for embryonic development and adult tissue homeostasis; however, the mechanisms that control this cell behavior are poorly understood. Using high-resolution live-cell imaging in chick neural tube, we uncover a form of cell sub...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2014-01, Vol.343 (6167), p.200-204
Hauptverfasser:	Das, Raman M., Storey, Kate G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abscission Actins Actins - metabolism adolescents Anatomy Animals Basic Helix-Loop-Helix Transcription Factors - metabolism brain Cadherins Cadherins - metabolism Carcinogenesis - pathology Cell cycle Cell Division Cell membranes cell nucleus Cell Polarity Centrosomes Chick Embryo Cilia Cilia - ultrastructure Cyclin-Dependent Kinase Inhibitor p27 - metabolism Embryology Embryonic cells Embryos Gene expression Homeostasis Individualized Instruction Mice Myosins - metabolism Nerve Tissue Proteins - metabolism Neural Tube - growth & development Neural Tube - metabolism Neurobiology Neurogenesis Neurons Neurons - cytology Neurons - metabolism Neurons - ultrastructure Studies vertebrates
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