A two-stage approach for measuring vascular water exchange and arterial transit time by diffusion-weighted perfusion MRI

Changes in the exchange rate of water across the blood‐brain barrier, denoted kw, may indicate blood‐brain barrier dysfunction before the leakage of large‐molecule contrast agents is observable. A previously proposed approach for measuring kw is to use diffusion‐weighted arterial spin labeling to me...

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Veröffentlicht in:	Magnetic resonance in medicine 2012-05, Vol.67 (5), p.1275-1284
Hauptverfasser:	St. Lawrence, Keith S., Owen, Daron, Wang, Danny J. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Flow Velocity - physiology Blood-Brain Barrier - physiology Body Water - metabolism Brain - physiology Cerebral Arteries - physiology Cerebrovascular Circulation - physiology Diffusion Magnetic Resonance Imaging - methods Humans Image Interpretation, Computer-Assisted - methods Magnetic Resonance Angiography - methods Reference Values Reproducibility of Results Sensitivity and Specificity
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