Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis： A case report
We have reported a case of hepatic adenomatosis associated with hormone replacement therapy （estrogen and progesterone） and hemosiderosis caused by excessive blood transfusion for the treatment of chronic myeloid leukemia. A 34-year-old woman was found to have several hepatic tumors on a routine med...
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| Veröffentlicht in: | World journal of gastroenterology : WJG 2006-01, Vol.12 (4), p.652-655 |
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| container_title | World journal of gastroenterology : WJG |
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| creator | Hagiwara, Satoshi Takagi, Hitoshi Kanda, Daisuke Sohara, Naondo Kakizaki, Satoru Katakai, Kenji Yoshinaga, Teruo Higuchi, Tsugio Nomoto, Kenichi Kuwano, Hiroyuki Mori, Masatomo |
| description | We have reported a case of hepatic adenomatosis associated with hormone replacement therapy （estrogen and progesterone） and hemosiderosis caused by excessive blood transfusion for the treatment of chronic myeloid leukemia. A 34-year-old woman was found to have several hepatic tumors on a routine medical examination. The general condition was good. Laboratory studies showed iron overload. Abdominal computed tomography and selective hepatic angiography showed several hypervascular tumors in the right lobe of the liver （up to 20 mm in diameter）. Since hepatocellular carcinoma could not be ruled out, subsegmental hepatectomy was performed. Histopathological examination of the surgical specimen showed hepatic adenomatosis with hemosiderosis. Both hormone replacement therapy and iron overload could be the cause of hepatic adenomatosis. |
| doi_str_mv | 10.3748/wjg.v12.i4.652 |
| format | Article |
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A 34-year-old woman was found to have several hepatic tumors on a routine medical examination. The general condition was good. Laboratory studies showed iron overload. Abdominal computed tomography and selective hepatic angiography showed several hypervascular tumors in the right lobe of the liver （up to 20 mm in diameter）. Since hepatocellular carcinoma could not be ruled out, subsegmental hepatectomy was performed. Histopathological examination of the surgical specimen showed hepatic adenomatosis with hemosiderosis. Both hormone replacement therapy and iron overload could be the cause of hepatic adenomatosis.</description><identifier>ISSN: 1007-9327</identifier><identifier>EISSN: 2219-2840</identifier><identifier>DOI: 10.3748/wjg.v12.i4.652</identifier><identifier>PMID: 16489686</identifier><language>eng</language><publisher>United States: Saiseikai Maebashi Hospital, 564-1 Kamishinden, Maebashi, Gunma 371-0821, Japan%Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa,Maebashi, Gunma 371-8511, Japan%Department of General Surgical Science, Gunma University Graduate School of Medicine, 3-39-15 Showa, Maebashi, Gunma 371-8511, Japan</publisher><subject>Adenoma - etiology ; Adenoma - pathology ; Adult ; Case Report ; Diagnosis, Differential ; Estrogen Replacement Therapy - adverse effects ; Female ; Hemosiderosis - complications ; Hemosiderosis - etiology ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy ; Liver Neoplasms - etiology ; Liver Neoplasms - pathology ; Transfusion Reaction ; Whole-Body Irradiation - adverse effects ; 含铁血黄素沉着症 ; 激素治疗 ; 肝肿瘤 ; 雌激素</subject><ispartof>World journal of gastroenterology : WJG, 2006-01, Vol.12 (4), p.652-655</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><rights>2006 Baishideng Publishing Group Co., Limited. All rights reserved. 2006</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/84123X/84123X.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066105/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066105/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16489686$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hagiwara, Satoshi</creatorcontrib><creatorcontrib>Takagi, Hitoshi</creatorcontrib><creatorcontrib>Kanda, Daisuke</creatorcontrib><creatorcontrib>Sohara, Naondo</creatorcontrib><creatorcontrib>Kakizaki, Satoru</creatorcontrib><creatorcontrib>Katakai, Kenji</creatorcontrib><creatorcontrib>Yoshinaga, Teruo</creatorcontrib><creatorcontrib>Higuchi, Tsugio</creatorcontrib><creatorcontrib>Nomoto, Kenichi</creatorcontrib><creatorcontrib>Kuwano, Hiroyuki</creatorcontrib><creatorcontrib>Mori, Masatomo</creatorcontrib><title>Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis： A case report</title><title>World journal of gastroenterology : WJG</title><addtitle>World Journal of Gastroenterology</addtitle><description>We have reported a case of hepatic adenomatosis associated with hormone replacement therapy （estrogen and progesterone） and hemosiderosis caused by excessive blood transfusion for the treatment of chronic myeloid leukemia. A 34-year-old woman was found to have several hepatic tumors on a routine medical examination. The general condition was good. Laboratory studies showed iron overload. Abdominal computed tomography and selective hepatic angiography showed several hypervascular tumors in the right lobe of the liver （up to 20 mm in diameter）. Since hepatocellular carcinoma could not be ruled out, subsegmental hepatectomy was performed. Histopathological examination of the surgical specimen showed hepatic adenomatosis with hemosiderosis. Both hormone replacement therapy and iron overload could be the cause of hepatic adenomatosis.</description><subject>Adenoma - etiology</subject><subject>Adenoma - pathology</subject><subject>Adult</subject><subject>Case Report</subject><subject>Diagnosis, Differential</subject><subject>Estrogen Replacement Therapy - adverse effects</subject><subject>Female</subject><subject>Hemosiderosis - complications</subject><subject>Hemosiderosis - etiology</subject><subject>Humans</subject><subject>Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy</subject><subject>Liver Neoplasms - etiology</subject><subject>Liver Neoplasms - pathology</subject><subject>Transfusion Reaction</subject><subject>Whole-Body Irradiation - adverse effects</subject><subject>含铁血黄素沉着症</subject><subject>激素治疗</subject><subject>肝肿瘤</subject><subject>雌激素</subject><issn>1007-9327</issn><issn>2219-2840</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkctu1DAUhi0EokNhyxJZiG3CseNx4g1SVbUUqRIbWFsnvkw8TOJgpx31VXgW3olXqIcZcVl54f9mf4S8ZlA3reje77eb-p7xOoharvkTsuKcqYp3Ap6SFQNoK9Xw9oy8yHkLwJtmzZ-TMyZFp2QnV8TcuBmXYChaN8URl5hDpphzNAEXZ-k-LAMdYhrj5Ghy8w6NG9200GVwCecHipOlgxuLz7p0cP_6-YNeUIP5tz6m5SV55nGX3avTeU6-Xl99ubypbj9__HR5cVuZRqmlMq1lDKxh0tu-620PVpnOeutgrTrVd6ZvvcDGcdV6JY1HYN54K0AgoJPNOflwzJ3v-tFZU1Ym3Ok5hRHTg44Y9P83Uxj0Jt5rAVIyWJeAd8eAPU4ep43exrs0lcm6fDMHkCCAH3rqo8yU9-bk_J8KBvpA5SDXhYoOQhcqxfDm32F_5ScMRfD2lDjEafM9lOoezTcfdk5zxgtCKZpHFDCanQ</recordid><startdate>20060128</startdate><enddate>20060128</enddate><creator>Hagiwara, Satoshi</creator><creator>Takagi, Hitoshi</creator><creator>Kanda, Daisuke</creator><creator>Sohara, Naondo</creator><creator>Kakizaki, Satoru</creator><creator>Katakai, Kenji</creator><creator>Yoshinaga, Teruo</creator><creator>Higuchi, Tsugio</creator><creator>Nomoto, Kenichi</creator><creator>Kuwano, Hiroyuki</creator><creator>Mori, Masatomo</creator><general>Saiseikai Maebashi Hospital, 564-1 Kamishinden, Maebashi, Gunma 371-0821, Japan%Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa,Maebashi, Gunma 371-8511, Japan%Department of General Surgical Science, Gunma University Graduate School of Medicine, 3-39-15 Showa, Maebashi, Gunma 371-8511, Japan</general><general>Baishideng Publishing Group Co., Limited</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope><scope>5PM</scope></search><sort><creationdate>20060128</creationdate><title>Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis： A case report</title><author>Hagiwara, Satoshi ; 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A 34-year-old woman was found to have several hepatic tumors on a routine medical examination. The general condition was good. Laboratory studies showed iron overload. Abdominal computed tomography and selective hepatic angiography showed several hypervascular tumors in the right lobe of the liver （up to 20 mm in diameter）. Since hepatocellular carcinoma could not be ruled out, subsegmental hepatectomy was performed. Histopathological examination of the surgical specimen showed hepatic adenomatosis with hemosiderosis. Both hormone replacement therapy and iron overload could be the cause of hepatic adenomatosis.</abstract><cop>United States</cop><pub>Saiseikai Maebashi Hospital, 564-1 Kamishinden, Maebashi, Gunma 371-0821, Japan%Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, 3-39-15 Showa,Maebashi, Gunma 371-8511, Japan%Department of General Surgical Science, Gunma University Graduate School of Medicine, 3-39-15 Showa, Maebashi, Gunma 371-8511, Japan</pub><pmid>16489686</pmid><doi>10.3748/wjg.v12.i4.652</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1007-9327 |
| ispartof | World journal of gastroenterology : WJG, 2006-01, Vol.12 (4), p.652-655 |
| issn | 1007-9327 2219-2840 |
| language | eng |
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| subjects | Adenoma - etiology Adenoma - pathology Adult Case Report Diagnosis, Differential Estrogen Replacement Therapy - adverse effects Female Hemosiderosis - complications Hemosiderosis - etiology Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy Liver Neoplasms - etiology Liver Neoplasms - pathology Transfusion Reaction Whole-Body Irradiation - adverse effects 含铁血黄素沉着症 激素治疗 肝肿瘤 雌激素 |
| title | Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis： A case report |
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