Detection of disseminated pancreatic cells by amplification of cytokeratin-19 with quantitative RT-PCR in blood, bone marrow and peritoneal lavage of pancreatic carcinoma patients

AIM： To evaluate the diagnostic potential of cytokeratin-19 （CK-19） mRNA for the detection of disseminated tumor cells in blood, bone marrow and peritoneal lavage in patients with ductal adenocarcinoma of the pancreas. METHODS： Sixty-eight patients with pancreatic cancer （/7 = 37）, chronic pancreati...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2007-01, Vol.13 (2), p.257-263
Hauptverfasser:	Hoffmann, Katrin, Kerner, Christiane, Wilfert, Wolfgang, Mueller, Marc, Thiery, Joachim, Hauss, Johann, Witzigmann, Helmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - analysis Biomarkers, Tumor - blood Bone Marrow - pathology Carcinoma, Pancreatic Ductal - diagnosis Carcinoma, Pancreatic Ductal - pathology Clinical Research Humans Keratin-19 - genetics Neoplastic Cells, Circulating - chemistry Neoplastic Cells, Circulating - pathology Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - pathology Peritoneal Lavage Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - analysis RNA, Messenger - blood RNA, Neoplasm - analysis RNA, Neoplasm - blood 细胞角蛋白胰腺炎腹腔灌洗
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