Synthesis of [11C]Bexarotene by Cu-Mediated [11C]Carbon Dioxide Fixation and Preliminary PET Imaging

Bexarotene (Targretin) is a retinoid X receptor (RXR) agonist that has applications for treatment of T cell lymphoma and proposed mechanisms of action in Alzheimer’s disease that have been the subject of recent controversy. Carbon-11 labeled bexarotene ([11C-carbonyl]4-[1-(3,5,5,8,8-pentamethyltetra...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	ACS medicinal chemistry letters 2014-06, Vol.5 (6), p.668-672
Hauptverfasser:	Rotstein, Benjamin H, Hooker, Jacob M, Woo, Jiyeon, Collier, Thomas Lee, Brady, Thomas J, Liang, Steven H, Vasdev, Neil
Format:	Artikel
Sprache:	eng
Schlagworte:	Letter
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!