Rationale for the use of upfront whole brain irradiation in patients with brain metastases from breast cancer

Breast cancer is the second most common cause of brain metastases and deserves particular attention in relation to current prolonged survival of patients with metastatic disease. Advances in both systemic therapies and brain local treatments (surgery and stereotactic radiosurgery) have led to a reap...

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Veröffentlicht in:	International journal of molecular sciences 2014-05, Vol.15 (5), p.8138-8152
Hauptverfasser:	Tallet, Agnes V, Azria, David, Le Rhun, Emilie, Barlesi, Fabrice, Carpentier, Antoine F, Gonçalves, Antony, Taillibert, Sophie, Dhermain, Frédéric, Spano, Jean-Philippe, Metellus, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Brain - pathology Brain - radiation effects Brain Neoplasms - pathology Brain Neoplasms - radiotherapy Brain Neoplasms - secondary Brain Neoplasms - therapy Breast - pathology Breast cancer Breast Neoplasms - pathology Cancer Clinical outcomes Combined Modality Therapy - methods Cranial Irradiation - methods Female Humans Life Sciences Metastasis Neurons and Cognition Radiation therapy Radiation-Sensitizing Agents - therapeutic use Review Survival Analysis
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