Risk factors for un-investigated dyspepsia among primary care patients in northern Nigeria

Background: Many risk factors have been speculated to be associated with uninvestigated dyspepsia amongst different population groups. Some of which have been subjected to epidemiological survey while others remain unevaluated. Objective: We evaluated some of the documented risk factors amongst pati...

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Veröffentlicht in:African health sciences 2013-01, Vol.13 (4), p.1007-1011
Hauptverfasser: Solomon, O.A, Ajayi, A.O
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Ajayi, A.O
description Background: Many risk factors have been speculated to be associated with uninvestigated dyspepsia amongst different population groups. Some of which have been subjected to epidemiological survey while others remain unevaluated. Objective: We evaluated some of the documented risk factors amongst patient presenting with uninvestigated dyspepsia and compared with a matched group without dyspepsia in a primary care setting. Methods: The study was a matched case controlled study. 103 consecutive patient aged between 18 and 50 years that presented with dyspepsia (cases) were enrolled. These were matched by age and sex with the same number of subjects without dyspepsia (controls). Data were collated using a structured questionnaire Odds ratios and p-values were used to determine the significance of documented categorical risk factors associated with dyspepsia using two by two tables. For risk factors that were continuous variables the means, standard deviations and p-values were used. Risk factors with their p-values
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Some of which have been subjected to epidemiological survey while others remain unevaluated. Objective: We evaluated some of the documented risk factors amongst patient presenting with uninvestigated dyspepsia and compared with a matched group without dyspepsia in a primary care setting. Methods: The study was a matched case controlled study. 103 consecutive patient aged between 18 and 50 years that presented with dyspepsia (cases) were enrolled. These were matched by age and sex with the same number of subjects without dyspepsia (controls). Data were collated using a structured questionnaire Odds ratios and p-values were used to determine the significance of documented categorical risk factors associated with dyspepsia using two by two tables. For risk factors that were continuous variables the means, standard deviations and p-values were used. Risk factors with their p-values &lt;0.2 were entered into logistic regression to identify those independently associated with dyspepsia. Result: H. pylori seropositivity was 22.3% and 13.6% among cases and controls respectively (p = 0.10). Pepper intake (p&lt;0.0001) and tea intake (p = 0.0002) and greater years of education (p = 0.0065) were significantly associated with dyspepsia. H. pylori seropositivity was not related to the risk of developing dyspepsia. Conclusion: Helicobacter pylori seropositivity was not found to be a significant contributor to risk of developing dyspepsia among the studied population contrary to general belief. Pepper intake, tea intake and greater years of education were found to significant contributors to dyspepsia.</description><identifier>ISSN: 1680-6905</identifier><identifier>EISSN: 1729-0503</identifier><identifier>EISSN: 1680-6905</identifier><identifier>DOI: 10.4314/ahs.v13i4.21</identifier><identifier>PMID: 24940325</identifier><language>eng</language><publisher>Uganda: Makerere University Medical School</publisher><subject>Adolescent ; Adult ; Case-Control Studies ; Dyspepsia ; Dyspepsia - epidemiology ; Dyspepsia - microbiology ; Enzyme-Linked Immunosorbent Assay ; Female ; Health and Medicine ; Helicobacter Infections - diagnosis ; Helicobacter Infections - epidemiology ; Helicobacter pylori ; Helicobacter pylori - isolation &amp; purification ; Humans ; Logistic Models ; Male ; Middle Aged ; Nigeria ; Nigeria - epidemiology ; Original ; Primary care ; Primary Health Care - methods ; Risk Factors ; Stomach ; Surveys and Questionnaires</subject><ispartof>African health sciences, 2013-01, Vol.13 (4), p.1007-1011</ispartof><rights>Copyright 2013 - African Health Sciences</rights><rights>Copyright © Makerere Medical School, Uganda 2013 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b513t-7593ef3d2d20a3a1382348f57e088124d4979bb7c918abd1ee1dcb3134fd072d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056499/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056499/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793,79426</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24940325$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Solomon, O.A</creatorcontrib><creatorcontrib>Ajayi, A.O</creatorcontrib><title>Risk factors for un-investigated dyspepsia among primary care patients in northern Nigeria</title><title>African health sciences</title><addtitle>Afr Health Sci</addtitle><description>Background: Many risk factors have been speculated to be associated with uninvestigated dyspepsia amongst different population groups. Some of which have been subjected to epidemiological survey while others remain unevaluated. Objective: We evaluated some of the documented risk factors amongst patient presenting with uninvestigated dyspepsia and compared with a matched group without dyspepsia in a primary care setting. Methods: The study was a matched case controlled study. 103 consecutive patient aged between 18 and 50 years that presented with dyspepsia (cases) were enrolled. These were matched by age and sex with the same number of subjects without dyspepsia (controls). Data were collated using a structured questionnaire Odds ratios and p-values were used to determine the significance of documented categorical risk factors associated with dyspepsia using two by two tables. For risk factors that were continuous variables the means, standard deviations and p-values were used. Risk factors with their p-values &lt;0.2 were entered into logistic regression to identify those independently associated with dyspepsia. Result: H. pylori seropositivity was 22.3% and 13.6% among cases and controls respectively (p = 0.10). Pepper intake (p&lt;0.0001) and tea intake (p = 0.0002) and greater years of education (p = 0.0065) were significantly associated with dyspepsia. H. pylori seropositivity was not related to the risk of developing dyspepsia. Conclusion: Helicobacter pylori seropositivity was not found to be a significant contributor to risk of developing dyspepsia among the studied population contrary to general belief. Pepper intake, tea intake and greater years of education were found to significant contributors to dyspepsia.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Case-Control Studies</subject><subject>Dyspepsia</subject><subject>Dyspepsia - epidemiology</subject><subject>Dyspepsia - microbiology</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Health and Medicine</subject><subject>Helicobacter Infections - diagnosis</subject><subject>Helicobacter Infections - epidemiology</subject><subject>Helicobacter pylori</subject><subject>Helicobacter pylori - isolation &amp; purification</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nigeria</subject><subject>Nigeria - epidemiology</subject><subject>Original</subject><subject>Primary care</subject><subject>Primary Health Care - methods</subject><subject>Risk Factors</subject><subject>Stomach</subject><subject>Surveys and Questionnaires</subject><issn>1680-6905</issn><issn>1729-0503</issn><issn>1680-6905</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>RBI</sourceid><sourceid>EIF</sourceid><recordid>eNqVkktv1DAUhS0EoqWwY40swYIFGXz9SOINEqp4SRVICDZsLCe-mXHJ2KmdDOq_xzDTEe2OlS3709E59x5CngJbSQHytd3k1Q6ElysO98gpNFxXTDFxv9zrllW1ZuqEPMr5kjFeg4aH5IRLLZng6pT8-OrzTzrYfo4p0yEmuoTKhx3m2a_tjI666zzhlL2ldhvDmk7Jb226pr1NSCc7ewxzpj7QENO8wRToZ7_G5O1j8mCwY8Ynh_OMfH__7tv5x-riy4dP528vqk6BmKtGaYGDcNxxZoUF0XIh20E1yNoWuHRSN7rrml5DazsHiOD6ToCQg2MNd-KMvNnrTku3RdcXP8mO5uDTROvN7Z_gN2Ydd0YyVUuti8CLg0CKV0tJbn75hAOiy4artm40MKYK9vIOtvW5x3G0AePyXygoUWJzxeqCPr-DXsYlhTKw24Kv9lSfYs7F3DEeMPOnBqbUwPytgeFQ8Gf_juQI3-y9AKs90Pk4-oBHoi-LMzePRXKToaiD-A34Ub95</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Solomon, O.A</creator><creator>Ajayi, A.O</creator><general>Makerere University Medical School</general><general>Makerere Medical School</general><scope>RBI</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130101</creationdate><title>Risk factors for un-investigated dyspepsia among primary care patients in northern Nigeria</title><author>Solomon, O.A ; Ajayi, A.O</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b513t-7593ef3d2d20a3a1382348f57e088124d4979bb7c918abd1ee1dcb3134fd072d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Case-Control Studies</topic><topic>Dyspepsia</topic><topic>Dyspepsia - epidemiology</topic><topic>Dyspepsia - microbiology</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Health and Medicine</topic><topic>Helicobacter Infections - diagnosis</topic><topic>Helicobacter Infections - epidemiology</topic><topic>Helicobacter pylori</topic><topic>Helicobacter pylori - isolation &amp; purification</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nigeria</topic><topic>Nigeria - epidemiology</topic><topic>Original</topic><topic>Primary care</topic><topic>Primary Health Care - methods</topic><topic>Risk Factors</topic><topic>Stomach</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Solomon, O.A</creatorcontrib><creatorcontrib>Ajayi, A.O</creatorcontrib><collection>Bioline International</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>African health sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Solomon, O.A</au><au>Ajayi, A.O</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk factors for un-investigated dyspepsia among primary care patients in northern Nigeria</atitle><jtitle>African health sciences</jtitle><addtitle>Afr Health Sci</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>13</volume><issue>4</issue><spage>1007</spage><epage>1011</epage><pages>1007-1011</pages><issn>1680-6905</issn><eissn>1729-0503</eissn><eissn>1680-6905</eissn><abstract>Background: Many risk factors have been speculated to be associated with uninvestigated dyspepsia amongst different population groups. Some of which have been subjected to epidemiological survey while others remain unevaluated. Objective: We evaluated some of the documented risk factors amongst patient presenting with uninvestigated dyspepsia and compared with a matched group without dyspepsia in a primary care setting. Methods: The study was a matched case controlled study. 103 consecutive patient aged between 18 and 50 years that presented with dyspepsia (cases) were enrolled. These were matched by age and sex with the same number of subjects without dyspepsia (controls). Data were collated using a structured questionnaire Odds ratios and p-values were used to determine the significance of documented categorical risk factors associated with dyspepsia using two by two tables. For risk factors that were continuous variables the means, standard deviations and p-values were used. Risk factors with their p-values &lt;0.2 were entered into logistic regression to identify those independently associated with dyspepsia. Result: H. pylori seropositivity was 22.3% and 13.6% among cases and controls respectively (p = 0.10). Pepper intake (p&lt;0.0001) and tea intake (p = 0.0002) and greater years of education (p = 0.0065) were significantly associated with dyspepsia. H. pylori seropositivity was not related to the risk of developing dyspepsia. Conclusion: Helicobacter pylori seropositivity was not found to be a significant contributor to risk of developing dyspepsia among the studied population contrary to general belief. Pepper intake, tea intake and greater years of education were found to significant contributors to dyspepsia.</abstract><cop>Uganda</cop><pub>Makerere University Medical School</pub><pmid>24940325</pmid><doi>10.4314/ahs.v13i4.21</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adult
Case-Control Studies
Dyspepsia
Dyspepsia - epidemiology
Dyspepsia - microbiology
Enzyme-Linked Immunosorbent Assay
Female
Health and Medicine
Helicobacter Infections - diagnosis
Helicobacter Infections - epidemiology
Helicobacter pylori
Helicobacter pylori - isolation & purification
Humans
Logistic Models
Male
Middle Aged
Nigeria
Nigeria - epidemiology
Original
Primary care
Primary Health Care - methods
Risk Factors
Stomach
Surveys and Questionnaires
title Risk factors for un-investigated dyspepsia among primary care patients in northern Nigeria
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