Obesity, rather than diet, drives epigenomics alterations in colonic epithelium resembling cancer progression

While obesity represents one of several risk factors for colorectal cancer in humans, the mechanistic underpinnings of this association remain unresolved. Environmental stimuli, including diet, can alter the epigenetic landscape of DNA cis-regulatory elements affecting gene expression and phenotype....

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Veröffentlicht in:	Cell metabolism 2014-04, Vol.19 (4), p.702-711
Hauptverfasser:	Li, Ruifang, Grimm, Sara A., Chrysovergis, Kaliopi, Kosak, Justin, Wang, Xingya, Du, Ying, Burkholder, Adam, Janardhan, Kyathanahalli, Mav, Deepak, Shah, Ruchir, Eling, Thomas E., Wade, Paul A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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