Isocitrate dehydrogenase mutation is associated with tumor location and magnetic resonance imaging characteristics in astrocytic neoplasms

The molecular subsets of glioma behave in biologically distinct ways. The present study detected isocitrate dehydrogenase (IDH) 1 and IDH2 mutations in glioma to analyze whether IDH-mutated gliomas are situated in certain preferential areas and to investigate their correlation with magnetic resonanc...

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Veröffentlicht in:	Oncology letters 2014-06, Vol.7 (6), p.1895-1902
Hauptverfasser:	QI, SONGTAO, YU, LEI, LI, HEZHEN, OU, YANGHUI, QIU, XIAOYU, DING, YANQING, HAN, HUIXIA, ZHANG, XUELIN
Format:	Artikel
Sprache:	eng
Schlagworte:	astrocytoma Brain cancer Dehydrogenases Deoxyribonucleic acid Development and progression DNA Edema Gene mutations Genetic aspects Glioma Gliomas Health aspects isocitrate dehydrogenase magnetic resonance imaging Medical prognosis Mutation NMR Nuclear magnetic resonance Oncology Oxidoreductases prognosis Studies Surgery tumor location Tumors
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