Clinical analysis of pulmonary infection in hemodialysis patients
The present study aimed to investigate the pathogen distribution and drug resistance of lung infections in hemodialysis to guide clinical empirical pharmacy. The clinical data of 116 hemodialysis patients with pulmonary infection were analyzed. The majority of the 82 pathogens isolated from the sput...
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| Veröffentlicht in: | Experimental and therapeutic medicine 2014-06, Vol.7 (6), p.1713-1717 |
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| container_title | Experimental and therapeutic medicine |
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| creator | REN, WEI PAN, HUIXUAN WANG, PENG LAN, LEI CHEN, WEI WANG, YAN NI, LIJUN PENG, LI |
| description | The present study aimed to investigate the pathogen distribution and drug resistance of lung infections in hemodialysis to guide clinical empirical pharmacy. The clinical data of 116 hemodialysis patients with pulmonary infection were analyzed. The majority of the 82 pathogens isolated from the sputa of patients were Gram-negative bacteria (accounting for 71.95%). The results of the drug sensitivity test suggested that Gram-negative bacilli had low resistance rates to piperacillin and tazobactam, imipenem and amikacin, while Gram-positive cocci had a low resistance rate to vancomycin. All resistance rates of the pathogens to other common antimicrobials were >50%. The pathogens resulting in lung infections in hemodialysis patients were mainly Gram-negative bacteria and were significantly resistant to various antibacterials. Results of the this study demonstrate that pathological examination should be performed as early as possible and effective antimicrobial agents should be chosen according to drug sensitivity test results. |
| doi_str_mv | 10.3892/etm.2014.1646 |
| format | Article |
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The clinical data of 116 hemodialysis patients with pulmonary infection were analyzed. The majority of the 82 pathogens isolated from the sputa of patients were Gram-negative bacteria (accounting for 71.95%). The results of the drug sensitivity test suggested that Gram-negative bacilli had low resistance rates to piperacillin and tazobactam, imipenem and amikacin, while Gram-positive cocci had a low resistance rate to vancomycin. All resistance rates of the pathogens to other common antimicrobials were >50%. The pathogens resulting in lung infections in hemodialysis patients were mainly Gram-negative bacteria and were significantly resistant to various antibacterials. Results of the this study demonstrate that pathological examination should be performed as early as possible and effective antimicrobial agents should be chosen according to drug sensitivity test results.</description><identifier>ISSN: 1792-0981</identifier><identifier>EISSN: 1792-1015</identifier><identifier>DOI: 10.3892/etm.2014.1646</identifier><identifier>PMID: 24926372</identifier><language>eng</language><publisher>Greece: D.A. Spandidos</publisher><subject>Accounting ; Age ; Antibiotics ; Arteriosclerosis ; Bacteria ; Diabetes ; Diagnosis ; Drug resistance ; drug sensitivity test ; E coli ; Gram-negative bacteria ; Gram-positive bacteria ; Health aspects ; Hemodialysis ; Hemodialysis patients ; Hypertension ; Infection ; Kidney diseases ; Lung diseases ; Lungs ; Medical diagnosis ; Medical prognosis ; Mortality ; Pathogens ; Patients ; pulmonary infection ; Risk factors ; sputum culture ; Streptococcus infections</subject><ispartof>Experimental and therapeutic medicine, 2014-06, Vol.7 (6), p.1713-1717</ispartof><rights>Copyright © 2014, Spandidos Publications</rights><rights>COPYRIGHT 2014 Spandidos Publications</rights><rights>Copyright Spandidos Publications UK Ltd. 2014</rights><rights>Copyright © 2014, Spandidos Publications 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c514t-19f2e13d80b1e67b11737de4830f2ad40c49e98ea03d7572084a948b9ae91c3c3</citedby><cites>FETCH-LOGICAL-c514t-19f2e13d80b1e67b11737de4830f2ad40c49e98ea03d7572084a948b9ae91c3c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043622/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043622/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24926372$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>REN, WEI</creatorcontrib><creatorcontrib>PAN, HUIXUAN</creatorcontrib><creatorcontrib>WANG, PENG</creatorcontrib><creatorcontrib>LAN, LEI</creatorcontrib><creatorcontrib>CHEN, WEI</creatorcontrib><creatorcontrib>WANG, YAN</creatorcontrib><creatorcontrib>NI, LIJUN</creatorcontrib><creatorcontrib>PENG, LI</creatorcontrib><title>Clinical analysis of pulmonary infection in hemodialysis patients</title><title>Experimental and therapeutic medicine</title><addtitle>Exp Ther Med</addtitle><description>The present study aimed to investigate the pathogen distribution and drug resistance of lung infections in hemodialysis to guide clinical empirical pharmacy. The clinical data of 116 hemodialysis patients with pulmonary infection were analyzed. The majority of the 82 pathogens isolated from the sputa of patients were Gram-negative bacteria (accounting for 71.95%). The results of the drug sensitivity test suggested that Gram-negative bacilli had low resistance rates to piperacillin and tazobactam, imipenem and amikacin, while Gram-positive cocci had a low resistance rate to vancomycin. All resistance rates of the pathogens to other common antimicrobials were >50%. The pathogens resulting in lung infections in hemodialysis patients were mainly Gram-negative bacteria and were significantly resistant to various antibacterials. Results of the this study demonstrate that pathological examination should be performed as early as possible and effective antimicrobial agents should be chosen according to drug sensitivity test results.</description><subject>Accounting</subject><subject>Age</subject><subject>Antibiotics</subject><subject>Arteriosclerosis</subject><subject>Bacteria</subject><subject>Diabetes</subject><subject>Diagnosis</subject><subject>Drug resistance</subject><subject>drug sensitivity test</subject><subject>E coli</subject><subject>Gram-negative bacteria</subject><subject>Gram-positive bacteria</subject><subject>Health aspects</subject><subject>Hemodialysis</subject><subject>Hemodialysis patients</subject><subject>Hypertension</subject><subject>Infection</subject><subject>Kidney diseases</subject><subject>Lung diseases</subject><subject>Lungs</subject><subject>Medical diagnosis</subject><subject>Medical prognosis</subject><subject>Mortality</subject><subject>Pathogens</subject><subject>Patients</subject><subject>pulmonary infection</subject><subject>Risk factors</subject><subject>sputum culture</subject><subject>Streptococcus infections</subject><issn>1792-0981</issn><issn>1792-1015</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNptkUtr3DAUhU1oaUKaZbfF0EW78VRXkvXYFIahLwh0k6yFRr5OFGTJtexC_n1lZjppSqWFLtJ3j6RzquoNkA1Tmn7EedhQAnwDgouz6gKkpg0QaF8ca6IVnFdXOT-QMloBSrWvqnPKNRVM0otquws-emdDbaMNj9nnOvX1uIQhRTs91j726GafYqnqexxS54_YaGePcc6vq5e9DRmvjutldfvl883uW3P94-v33fa6cS3wuQHdUwTWKbIHFHIPIJnskCtGemo7ThzXqBVawjrZSkoUt5qrvbaowTHHLqtPB91x2Q_YuXL3ZIMZJz-Uh5pkvXl-Ev29uUu_DCecCUqLwIejwJR-LphnM_jsMAQbMS3ZgKKi1ZwqXtB3_6APaZmKQYXSbDVYMPFE3dmApjiVyr1uFTVbTpRUjCtSqM1_qDI7HLxLEXtf9p81NIcGN6WcJ-xPfwRi1thNid2ssZs19sK__duYE_0n5AK8PwB5tLHzXconpig1RDZENCCBsd8IEbPd</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>REN, WEI</creator><creator>PAN, HUIXUAN</creator><creator>WANG, PENG</creator><creator>LAN, LEI</creator><creator>CHEN, WEI</creator><creator>WANG, YAN</creator><creator>NI, LIJUN</creator><creator>PENG, LI</creator><general>D.A. 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The clinical data of 116 hemodialysis patients with pulmonary infection were analyzed. The majority of the 82 pathogens isolated from the sputa of patients were Gram-negative bacteria (accounting for 71.95%). The results of the drug sensitivity test suggested that Gram-negative bacilli had low resistance rates to piperacillin and tazobactam, imipenem and amikacin, while Gram-positive cocci had a low resistance rate to vancomycin. All resistance rates of the pathogens to other common antimicrobials were >50%. The pathogens resulting in lung infections in hemodialysis patients were mainly Gram-negative bacteria and were significantly resistant to various antibacterials. Results of the this study demonstrate that pathological examination should be performed as early as possible and effective antimicrobial agents should be chosen according to drug sensitivity test results.</abstract><cop>Greece</cop><pub>D.A. 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| ispartof | Experimental and therapeutic medicine, 2014-06, Vol.7 (6), p.1713-1717 |
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| subjects | Accounting Age Antibiotics Arteriosclerosis Bacteria Diabetes Diagnosis Drug resistance drug sensitivity test E coli Gram-negative bacteria Gram-positive bacteria Health aspects Hemodialysis Hemodialysis patients Hypertension Infection Kidney diseases Lung diseases Lungs Medical diagnosis Medical prognosis Mortality Pathogens Patients pulmonary infection Risk factors sputum culture Streptococcus infections |
| title | Clinical analysis of pulmonary infection in hemodialysis patients |
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