Degeneration and Dysfunction of Retinal Neurons in Acute Ocular Hypertensive Rats: Involvement of Calpains

Retinal ischemic diseases primarily lead to damage of the inner retinal neurons. Electrophysiological studies also suggest impairment of the inner retinal neurons. Our recent studies with acute ocular hypertensive rats confirmed damage predominantly in the inner retinal layer along with the ganglion...

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Veröffentlicht in:	Journal of ocular pharmacology and therapeutics 2014-06, Vol.30 (5), p.419-428
Hauptverfasser:	SUZUKI, Rie, OKA, Takayuki, TAMADA, Yoshiyuki, SHEARER, Thomas R, AZUMA, Mitsuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Calpain - antagonists & inhibitors Calpain - metabolism Carbamates - pharmacology Carbamates - therapeutic use Cardiology. Vascular system Male Medical sciences Ocular Hypertension - drug therapy Ocular Hypertension - metabolism Ocular Hypertension - pathology Original Rats Rats, Sprague-Dawley Retinal Degeneration - drug therapy Retinal Degeneration - metabolism Retinal Degeneration - pathology Retinal Neurons - drug effects Retinal Neurons - metabolism Retinal Neurons - pathology
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