B7-H3 overexpression in pancreatic cancer promotes tumor progression

B7-H3, a member of the B7-family molecules, plays an important role in adaptive immune responses. In addition, B7-H3 is also expressed in several types of human cancers and is correlated with the poor outcome of cancer patients. However, its exact role in cancer is not known. In the present study, w...

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Veröffentlicht in:	International journal of molecular medicine 2013-02, Vol.31 (2), p.283-291
Hauptverfasser:	ZHAO, XIN, LI, DE-CHUN, ZHU, XIN-GUO, GAN, WEN-JUAN, LI, ZHI, XIONG, FENG, ZHANG, ZI-XIANG, ZHANG, GUANG-BO, ZHANG, XUE-GUANG, ZHAO, HUA
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B7 Antigens - analysis B7 Antigens - genetics B7-H3 Cancer therapies Cell growth Cell Line, Tumor Cell Proliferation Enzymes Gene Expression Regulation, Neoplastic Humans Infections invasiveness Laboratories Male Metastasis Mice Mice, Inbred BALB C Mice, Nude migration Motility Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Pancreas - metabolism Pancreas - pathology Pancreatic cancer Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology progression Proteins RNA interference Studies Surgery Tumors Up-Regulation
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