Polypeptide N-acetylgalactosaminyltransferase 2 regulates cellular metastasis-associated behavior in gastric cancer

Aberrant glycosylation of cell surface glycoprotein due to specific alterations of glycosyltransferase activity is usually associated with invasion and metastasis of cancer, particularly of gastric carcinomas. Polypeptide N-acetylgalactosaminyltransferase 2 (ppGalNAc-T2), which catalyzes initiation...

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Veröffentlicht in:	International journal of molecular medicine 2012-12, Vol.30 (6), p.1267-1274
Hauptverfasser:	HUA, DONG, SHEN, LI, XU, LAN, JIANG, ZHI, ZHOU, YINGHUI, YUE, AIHUAN, ZOU, SHITAO, CHENG, ZHIHONG, WU, SHILIANG
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Cell Adhesion Cell growth Cell Line, Tumor Cell Movement Cell Proliferation Cell Survival Cloning Enzymes Gastric cancer Gene Expression Gene Knockdown Techniques Growth factors Humans Leukemia Matrix Metalloproteinase 14 - genetics Matrix Metalloproteinase 14 - metabolism Matrix Metalloproteinase 2 - genetics Matrix Metalloproteinase 2 - metabolism matrix metalloproteinase-2 Metastasis N-Acetylgalactosaminyltransferases - genetics N-Acetylgalactosaminyltransferases - metabolism N-Acetylgalactosaminyltransferases - physiology Ovarian cancer Polypeptide N-acetylgalactosaminyltransferase polypeptide N-acetylgalactosaminyltransferase 2 Polypeptides Proteins Stomach Neoplasms Studies Transforming Growth Factor beta1 - genetics Transforming Growth Factor beta1 - metabolism transforming growth factor-β1
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