Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70

Hsp70 is often overexpressed in cancer cells, and the selective cellular survival advantage that it confers may contribute to the process of tumour formation. Thus, the pharmacological manipulation of Hsp70 levels in cancer cells may be an effective means of preventing the progression of tumours. We...

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Veröffentlicht in:Cell death & disease 2014-01, Vol.5 (1), p.e1027-e1027
Hauptverfasser: Endo, H, Yano, M, Okumura, Y, Kido, H
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Sprache:eng
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