Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity

The level of IL-3 mRNA, a major cytokine for development and survival of basophils, is reportedly not elevated in CRS nasal and polyp tissue,13 a conclusion confirmed in a microarray analysis done by our group.14 However, as supported by the presence of basophils in IL-3-deficient mice,15 these cell...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2014-06, Vol.133 (6), p.1759-1763
Hauptverfasser:	Mahdavinia, Mahboobeh, MD, PhD, Carter, Roderick G., BS, Ocampo, Christopher J., MD, PhD, Stevens, Whitney, MD, PhD, Kato, Atsushi, PhD, Tan, Bruce K., MD, Kern, Robert C., MD, Conley, David B., MD, Chandra, Rakesh, MD, Hulse, Kathryn E., PhD, Suh, Lydia A., MSc, Norton, James E., MSc, Peters, Anju T., MD, Grammer, Leslie C., MD, Schwartz, Lawrence B., MD, PhD, Schleimer, Robert P., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Allergy and Immunology Basophils - immunology Chronic illnesses Cytokines Disease Eosinophils - immunology Humans Nasal Polyps - complications Nasal Polyps - immunology Respiratory Mucosa - immunology Respiratory Mucosa - pathology Rhinitis - complications Sinusitis - complications
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