Comparative Study of Antibiofilm Activity of Copper Oxide and Iron Oxide Nanoparticles Against Multidrug Resistant Biofilm Forming Uropathogens

The effectiveness of the metal oxide nanoparticles viz. CuO and Fe₂O₃as antibacterial agents against multidrug resistant biofilm forming bacteria was evaluated. CuO nanoparticles were also experimented for antibiofilm and time kill assay. The CuO displayed maximum antibacterial activity with zone of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Indian journal of microbiology 2014-09, Vol.54 (3), p.365-368
Hauptverfasser:	Agarwala, Munin, Choudhury, Bula, Yadav, R. N. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial agents antibacterial properties Antibiotics Bacteria biofilm Biofilms Biomedical and Life Sciences Catheters Comparative studies Copper cupric oxide dose response E coli Escherichia coli Gram-negative bacteria Gram-positive bacteria Iron oxides Life Sciences Medical Microbiology methicillin Microbiology multiple drug resistance Nanoparticles Short Communication Staphylococcus aureus Staphylococcus infections toxicity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The effectiveness of the metal oxide nanoparticles viz. CuO and Fe₂O₃as antibacterial agents against multidrug resistant biofilm forming bacteria was evaluated. CuO nanoparticles were also experimented for antibiofilm and time kill assay. The CuO displayed maximum antibacterial activity with zone of inhibition of (22 ± 1) mm against methicillin resistant Staphylococcus aureus (MRSA) followed by Escherichia coli (18 ± 1) mm. The Fe₂O₃showed the zone of inhibition against MRSA of (14 ± 1) mm followed by E. coli (12 ± 1) mm. CuO proved to be more toxic than Fe₂O₃nanoparticles showing significantly high antibacterial activity and found to possess dose dependent antibiofilm properties.
ISSN:	0046-8991 0973-7715
DOI:	10.1007/s12088-014-0462-z