Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress

Background Chronic metabolic overload leads to insulin resistance in a variety of tissues. It has been shown that exposure to saturated fatty acid palmitate can cause insulin resistance in skeletal muscle cells. Fatty acid induced synthesis of ceramide is considered to be one of the major causes for...

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Veröffentlicht in:	SpringerPlus 2014-05, Vol.3 (1), p.255-255, Article 255
Hauptverfasser:	Verma, Mahesh Kumar, Yateesh, Aggunda Nagaraju, Neelima, Korrapati, Pawar, Niketa, Sandhya, Kandoor, Poornima, Jayaram, Lakshmi, Mudigere N, Yogeshwari, Sivakumaran, Pallavi, Puttrevana M, Oommen, Anup M, Somesh, Baggavalli P, Jagannath, Madanahalli R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Humanities and Social Sciences multidisciplinary Science Science (multidisciplinary)
Online-Zugang:	Volltext
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