Group 1B phospholipase A2 inactivation suppresses atherosclerosis and metabolic diseases in LDL receptor-deficient mice

Abstract Objective Previous studies have shown that inactivation of the group 1B phospholipase A2 (Pla2g1b) suppresses diet-induced obesity, hyperglycemia, insulin resistance, and hyperlipidemia in C57BL/6 mice. A possible influence of Pla2g1b inactivation on atherosclerosis has not been addressed p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Atherosclerosis 2014-06, Vol.234 (2), p.377-380
Hauptverfasser:	Hollie, Norris I, Konaniah, Eddy S, Goodin, Colleen, Hui, David Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis Atherosclerosis - blood Atherosclerosis - enzymology Atherosclerosis - genetics Atherosclerosis - prevention & control Biomarkers - blood Blood Glucose - metabolism Cardiovascular Dietary Fats Disease Models, Animal Energy Intake Glucose tolerance Group IB Phospholipases A2 - deficiency Group IB Phospholipases A2 - genetics Hyperglycemia - blood Hyperglycemia - enzymology Hyperglycemia - genetics Hyperglycemia - prevention & control Hyperinsulinism - blood Hyperinsulinism - enzymology Hyperinsulinism - genetics Hyperinsulinism - prevention & control Hyperlipidemias - blood Hyperlipidemias - enzymology Hyperlipidemias - genetics Hyperlipidemias - prevention & control Insulin - blood Lipid and lipoprotein metabolism Lipids - blood Male Mice, Inbred C57BL Mice, Knockout Phospholipase Receptors, LDL - deficiency Receptors, LDL - genetics Weight Gain
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!