Circulating TSLP associates with decreased wheezing in non-atopic preschool children: data from the URECA birth cohort

Summary Background Mouse models of atopic march suggest that systemic, skin‐derived thymic stromal lymphopoietin (TSLP) mediates progression from eczema to asthma. Objective We investigated whether circulating TSLP is associated with eczema, allergic sensitization, or recurrent wheezing in young chi...

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Veröffentlicht in:	Clinical and experimental allergy 2014-06, Vol.44 (6), p.851-857
Hauptverfasser:	Demehri, S., Yockey, L. J., Visness, C. M., Jaffee, K. F., Turkoz, A., Wood, R. A., O'Connor, G. T., Kattan, M., Gern, J. E., Gergen, P. J., Holtzman, M., Bloomberg, G., Kopan, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology atopy birth cohort Child, Preschool Cytokines - blood Eczema - blood Eczema - etiology Female Humans Hypersensitivity - blood Hypersensitivity - etiology Infant Male Odds Ratio preschool wheeze Prospective Studies recurrent wheeze Respiratory Sounds - etiology TSLP URECA
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