Naturally Occurring Compounds Elicit HIV-1 Replication in Chronically Infected Promonocytic Cells

Since antiretroviral therapy suppresses but does not eradicate HIV-1 infection, methods to purge viral reservoirs are required. Many strategies involve the reactivation of chronically HIV infected cells to induce the expression of integrated viral genome. In this study, five bioactive compounds, the...

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Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-6
Hauptverfasser:	Barquero, Andrea Alejandra, Dávola, María Eugenia, Riva, Diego Ariel, Mersich, Susana Esther, Alché, Laura Edith
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Antigens Biological Factors - pharmacology Biological products Cell Line Cell Line, Tumor Cholestanones - pharmacology Curcumin - pharmacology Cytokines Development and progression DNA Replication - drug effects Growth hormones Health aspects HIV HIV infection HIV Infections - metabolism HIV Infections - virology HIV-1 - drug effects Human immunodeficiency virus Human immunodeficiency virus 1 Humans Interleukin-6 - pharmacology Limonins - pharmacology Masoprocol - pharmacology Monocytes - metabolism Monocytes - virology Plant Extracts - pharmacology Reactive Oxygen Species - metabolism Statistical analysis Stigmasterol - analogs & derivatives Stigmasterol - pharmacology Tumor Necrosis Factor-alpha - metabolism U937 Cells Virus Replication - drug effects
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