A comparison of the modified Tokuhashi and Tomita scores in determining prognosis for patients afflicted with spinal metastasis
Background The prognosis of patients with spinal metastasis is not very promising and hard to predict. It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survi...
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Veröffentlicht in: | Canadian Journal of Surgery 2014-06, Vol.57 (3), p.188-193 |
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description | Background The prognosis of patients with spinal metastasis is not very promising and hard to predict. It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survival. Methods We retrospectively reviewed the data of all patients treated for spinal metastasis between March 2003 and March 2012 in our centre. We computed the Tokuhashi and Tomita scores and compared them with documented patient survival. The 2 scores were also compared with one another. Results We identified 128 patients with spinal metastasis. The average survival of patients with predicted poor, average and good prognosis was 5, 17 and 25 months, respectively for the modified Tokuhashi score and 3, 16 and 19 months, respectively, for the Tomita score. Poor, average and good prognosis predictions differed significantly from one another for all 3 categories for the Tokuhashi score (all p < 0.05). There was no significant difference in the moderate and good prognoses for the Tomita score ( p = 0.15). When comparing both scores, we obtained a weighted ? of 0.4489 (standard deviation 0.0568, 95% confidence interval 0.3376–0.5602), demonstrating moderate agreement between scores. Conclusion Both scores have merit for use in a clinical setting and can be used as tools to help determine treatment choice. The modified Tokuhashi score had better accuracy in determining actual survival. |
doi_str_mv | 10.1503/cjs.012013 |
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It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survival. Methods We retrospectively reviewed the data of all patients treated for spinal metastasis between March 2003 and March 2012 in our centre. We computed the Tokuhashi and Tomita scores and compared them with documented patient survival. The 2 scores were also compared with one another. Results We identified 128 patients with spinal metastasis. The average survival of patients with predicted poor, average and good prognosis was 5, 17 and 25 months, respectively for the modified Tokuhashi score and 3, 16 and 19 months, respectively, for the Tomita score. Poor, average and good prognosis predictions differed significantly from one another for all 3 categories for the Tokuhashi score (all p < 0.05). There was no significant difference in the moderate and good prognoses for the Tomita score ( p = 0.15). When comparing both scores, we obtained a weighted ? of 0.4489 (standard deviation 0.0568, 95% confidence interval 0.3376–0.5602), demonstrating moderate agreement between scores. Conclusion Both scores have merit for use in a clinical setting and can be used as tools to help determine treatment choice. The modified Tokuhashi score had better accuracy in determining actual survival.</description><identifier>ISSN: 0008-428X</identifier><identifier>EISSN: 1488-2310</identifier><identifier>DOI: 10.1503/cjs.012013</identifier><identifier>PMID: 24869611</identifier><identifier>CODEN: CJSUAX</identifier><language>eng</language><publisher>Canada: CMA Joule Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cancer ; Care and treatment ; Chemotherapy ; Decision Support Techniques ; Effectiveness ; Female ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Male ; Medical prognosis ; Metastasis ; Middle Aged ; Prognosis ; Radiotherapy ; Retrospective Studies ; Severity of Illness Index ; Spinal Neoplasms - mortality ; Spinal Neoplasms - secondary ; Spinal Neoplasms - therapy ; Standard scores ; Studies ; Surgery ; Survival analysis ; Survival Rate</subject><ispartof>Canadian Journal of Surgery, 2014-06, Vol.57 (3), p.188-193</ispartof><rights>Canadian Medical Association</rights><rights>COPYRIGHT 2014 CMA Joule Inc.</rights><rights>Copyright Canadian Medical Association Jun 2014</rights><rights>2014 Canadian Medical Association 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c658t-1acc615e03e455d88d4f1dee4a309803e59338a18a597752ac47ea320a9fd7263</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035401/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035401/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24869611$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aoude, Ahmed, MD, MEng</creatorcontrib><creatorcontrib>Amiot, Louis-Philippe, MD, MSc (Eng)</creatorcontrib><title>A comparison of the modified Tokuhashi and Tomita scores in determining prognosis for patients afflicted with spinal metastasis</title><title>Canadian Journal of Surgery</title><addtitle>Can J Surg</addtitle><description>Background The prognosis of patients with spinal metastasis is not very promising and hard to predict. It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survival. Methods We retrospectively reviewed the data of all patients treated for spinal metastasis between March 2003 and March 2012 in our centre. We computed the Tokuhashi and Tomita scores and compared them with documented patient survival. The 2 scores were also compared with one another. Results We identified 128 patients with spinal metastasis. The average survival of patients with predicted poor, average and good prognosis was 5, 17 and 25 months, respectively for the modified Tokuhashi score and 3, 16 and 19 months, respectively, for the Tomita score. Poor, average and good prognosis predictions differed significantly from one another for all 3 categories for the Tokuhashi score (all p < 0.05). There was no significant difference in the moderate and good prognoses for the Tomita score ( p = 0.15). When comparing both scores, we obtained a weighted ? of 0.4489 (standard deviation 0.0568, 95% confidence interval 0.3376–0.5602), demonstrating moderate agreement between scores. Conclusion Both scores have merit for use in a clinical setting and can be used as tools to help determine treatment choice. The modified Tokuhashi score had better accuracy in determining actual survival.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cancer</subject><subject>Care and treatment</subject><subject>Chemotherapy</subject><subject>Decision Support Techniques</subject><subject>Effectiveness</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Kaplan-Meier Estimate</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Prognosis</subject><subject>Radiotherapy</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><subject>Spinal Neoplasms - mortality</subject><subject>Spinal Neoplasms - secondary</subject><subject>Spinal Neoplasms - therapy</subject><subject>Standard scores</subject><subject>Studies</subject><subject>Surgery</subject><subject>Survival analysis</subject><subject>Survival Rate</subject><issn>0008-428X</issn><issn>1488-2310</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptk11v0zAUhiMEYqNwww9AFpMQIKXYcZwmN0jVxMekCS42JO4s45w07hI783EGu-Kv49CxtqiyJcvHj18f-7xOkueMzpmg_J1e45yyjDL-IDlmeVmmGWf0YXJMKS3TPCu_HyVPENeUMsrz6nFylOVlURWMHSe_l0S7flDeoLPENSS0QHpXm8ZATS7d1dgqbA1Rdpr1JiiC2nlAYiypIYDvjTV2RQbvVtahQdI4TwYVDNiARDVNZ3SIWj9NaAkOxqqO9BAUxm7wafKoUR3Cs7txlnz7-OHy9HN6_vXT2enyPNWFKEPKlNYFE0A55ELUZVnnDasBcsVpVcaoqDgvFSuVqBYLkSmdL0DxjKqqqRdZwWfJ-43uMP7oodYxOa86OXjTK38rnTJyf8WaVq7cjcwpF3l82lny-k7Au-sRMMjeoIauUxbciJKJmIkoRDWhJ_-hazf6eO-_VHx2wfhiS61UB9LYxsVz9SQql3yRRTHOskilB6gVWIhJOguNieE9_uUBXg_mWu5C8wNQbDX0Rh9UfbO3ITIBfoWVGhHl2cWXffbVDtuC6kKLrhuDcRb3wbcbUHuH6KG5rwajcjK2jMaWG2NH-MVu_e7Rf07eFhiii24MeKm76Eytuiu4BdxWQGImqbyY_sb0NVguKC0E538AA1EFuw</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>Aoude, Ahmed, MD, MEng</creator><creator>Amiot, Louis-Philippe, MD, MSc (Eng)</creator><general>CMA Joule Inc</general><general>CMA Impact, Inc</general><general>Canadian Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISN</scope><scope>3V.</scope><scope>4T-</scope><scope>4U-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FQ</scope><scope>8FV</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M3G</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140601</creationdate><title>A comparison of the modified Tokuhashi and Tomita scores in determining prognosis for patients afflicted with spinal metastasis</title><author>Aoude, Ahmed, MD, MEng ; Amiot, Louis-Philippe, MD, MSc (Eng)</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c658t-1acc615e03e455d88d4f1dee4a309803e59338a18a597752ac47ea320a9fd7263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cancer</topic><topic>Care and treatment</topic><topic>Chemotherapy</topic><topic>Decision Support Techniques</topic><topic>Effectiveness</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Kaplan-Meier Estimate</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Prognosis</topic><topic>Radiotherapy</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><topic>Spinal Neoplasms - mortality</topic><topic>Spinal Neoplasms - secondary</topic><topic>Spinal Neoplasms - therapy</topic><topic>Standard scores</topic><topic>Studies</topic><topic>Surgery</topic><topic>Survival analysis</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aoude, Ahmed, MD, MEng</creatorcontrib><creatorcontrib>Amiot, Louis-Philippe, MD, MSc (Eng)</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Canada</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Canadian Business & Current Affairs Database</collection><collection>Canadian Business & Current Affairs Database (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>CBCA Reference & Current Events</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Canadian Journal of Surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aoude, Ahmed, MD, MEng</au><au>Amiot, Louis-Philippe, MD, MSc (Eng)</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparison of the modified Tokuhashi and Tomita scores in determining prognosis for patients afflicted with spinal metastasis</atitle><jtitle>Canadian Journal of Surgery</jtitle><addtitle>Can J Surg</addtitle><date>2014-06-01</date><risdate>2014</risdate><volume>57</volume><issue>3</issue><spage>188</spage><epage>193</epage><pages>188-193</pages><issn>0008-428X</issn><eissn>1488-2310</eissn><coden>CJSUAX</coden><abstract>Background The prognosis of patients with spinal metastasis is not very promising and hard to predict. It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survival. Methods We retrospectively reviewed the data of all patients treated for spinal metastasis between March 2003 and March 2012 in our centre. We computed the Tokuhashi and Tomita scores and compared them with documented patient survival. The 2 scores were also compared with one another. Results We identified 128 patients with spinal metastasis. The average survival of patients with predicted poor, average and good prognosis was 5, 17 and 25 months, respectively for the modified Tokuhashi score and 3, 16 and 19 months, respectively, for the Tomita score. Poor, average and good prognosis predictions differed significantly from one another for all 3 categories for the Tokuhashi score (all p < 0.05). There was no significant difference in the moderate and good prognoses for the Tomita score ( p = 0.15). When comparing both scores, we obtained a weighted ? of 0.4489 (standard deviation 0.0568, 95% confidence interval 0.3376–0.5602), demonstrating moderate agreement between scores. Conclusion Both scores have merit for use in a clinical setting and can be used as tools to help determine treatment choice. The modified Tokuhashi score had better accuracy in determining actual survival.</abstract><cop>Canada</cop><pub>CMA Joule Inc</pub><pmid>24869611</pmid><doi>10.1503/cjs.012013</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Cancer Care and treatment Chemotherapy Decision Support Techniques Effectiveness Female Follow-Up Studies Humans Kaplan-Meier Estimate Male Medical prognosis Metastasis Middle Aged Prognosis Radiotherapy Retrospective Studies Severity of Illness Index Spinal Neoplasms - mortality Spinal Neoplasms - secondary Spinal Neoplasms - therapy Standard scores Studies Surgery Survival analysis Survival Rate |
title | A comparison of the modified Tokuhashi and Tomita scores in determining prognosis for patients afflicted with spinal metastasis |
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