A comparison of the modified Tokuhashi and Tomita scores in determining prognosis for patients afflicted with spinal metastasis

Background The prognosis of patients with spinal metastasis is not very promising and hard to predict. It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survi...

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Veröffentlicht in:Canadian Journal of Surgery 2014-06, Vol.57 (3), p.188-193
Hauptverfasser: Aoude, Ahmed, MD, MEng, Amiot, Louis-Philippe, MD, MSc (Eng)
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Amiot, Louis-Philippe, MD, MSc (Eng)
description Background The prognosis of patients with spinal metastasis is not very promising and hard to predict. It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survival. Methods We retrospectively reviewed the data of all patients treated for spinal metastasis between March 2003 and March 2012 in our centre. We computed the Tokuhashi and Tomita scores and compared them with documented patient survival. The 2 scores were also compared with one another. Results We identified 128 patients with spinal metastasis. The average survival of patients with predicted poor, average and good prognosis was 5, 17 and 25 months, respectively for the modified Tokuhashi score and 3, 16 and 19 months, respectively, for the Tomita score. Poor, average and good prognosis predictions differed significantly from one another for all 3 categories for the Tokuhashi score (all p < 0.05). There was no significant difference in the moderate and good prognoses for the Tomita score ( p = 0.15). When comparing both scores, we obtained a weighted ? of 0.4489 (standard deviation 0.0568, 95% confidence interval 0.3376–0.5602), demonstrating moderate agreement between scores. Conclusion Both scores have merit for use in a clinical setting and can be used as tools to help determine treatment choice. The modified Tokuhashi score had better accuracy in determining actual survival.
doi_str_mv 10.1503/cjs.012013
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It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survival. Methods We retrospectively reviewed the data of all patients treated for spinal metastasis between March 2003 and March 2012 in our centre. We computed the Tokuhashi and Tomita scores and compared them with documented patient survival. The 2 scores were also compared with one another. Results We identified 128 patients with spinal metastasis. The average survival of patients with predicted poor, average and good prognosis was 5, 17 and 25 months, respectively for the modified Tokuhashi score and 3, 16 and 19 months, respectively, for the Tomita score. Poor, average and good prognosis predictions differed significantly from one another for all 3 categories for the Tokuhashi score (all p &lt; 0.05). There was no significant difference in the moderate and good prognoses for the Tomita score ( p = 0.15). When comparing both scores, we obtained a weighted ? of 0.4489 (standard deviation 0.0568, 95% confidence interval 0.3376–0.5602), demonstrating moderate agreement between scores. Conclusion Both scores have merit for use in a clinical setting and can be used as tools to help determine treatment choice. The modified Tokuhashi score had better accuracy in determining actual survival.</description><identifier>ISSN: 0008-428X</identifier><identifier>EISSN: 1488-2310</identifier><identifier>DOI: 10.1503/cjs.012013</identifier><identifier>PMID: 24869611</identifier><identifier>CODEN: CJSUAX</identifier><language>eng</language><publisher>Canada: CMA Joule Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cancer ; Care and treatment ; Chemotherapy ; Decision Support Techniques ; Effectiveness ; Female ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Male ; Medical prognosis ; Metastasis ; Middle Aged ; Prognosis ; Radiotherapy ; Retrospective Studies ; Severity of Illness Index ; Spinal Neoplasms - mortality ; Spinal Neoplasms - secondary ; Spinal Neoplasms - therapy ; Standard scores ; Studies ; Surgery ; Survival analysis ; Survival Rate</subject><ispartof>Canadian Journal of Surgery, 2014-06, Vol.57 (3), p.188-193</ispartof><rights>Canadian Medical Association</rights><rights>COPYRIGHT 2014 CMA Joule Inc.</rights><rights>Copyright Canadian Medical Association Jun 2014</rights><rights>2014 Canadian Medical Association 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c658t-1acc615e03e455d88d4f1dee4a309803e59338a18a597752ac47ea320a9fd7263</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035401/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035401/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24869611$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aoude, Ahmed, MD, MEng</creatorcontrib><creatorcontrib>Amiot, Louis-Philippe, MD, MSc (Eng)</creatorcontrib><title>A comparison of the modified Tokuhashi and Tomita scores in determining prognosis for patients afflicted with spinal metastasis</title><title>Canadian Journal of Surgery</title><addtitle>Can J Surg</addtitle><description>Background The prognosis of patients with spinal metastasis is not very promising and hard to predict. It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survival. Methods We retrospectively reviewed the data of all patients treated for spinal metastasis between March 2003 and March 2012 in our centre. We computed the Tokuhashi and Tomita scores and compared them with documented patient survival. The 2 scores were also compared with one another. Results We identified 128 patients with spinal metastasis. The average survival of patients with predicted poor, average and good prognosis was 5, 17 and 25 months, respectively for the modified Tokuhashi score and 3, 16 and 19 months, respectively, for the Tomita score. Poor, average and good prognosis predictions differed significantly from one another for all 3 categories for the Tokuhashi score (all p &lt; 0.05). There was no significant difference in the moderate and good prognoses for the Tomita score ( p = 0.15). When comparing both scores, we obtained a weighted ? of 0.4489 (standard deviation 0.0568, 95% confidence interval 0.3376–0.5602), demonstrating moderate agreement between scores. Conclusion Both scores have merit for use in a clinical setting and can be used as tools to help determine treatment choice. 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It is for this reason that scoring systems, such as the modified Tokuhashi and Tomita scores, have been created. We sought to determine the effectiveness of these scores in predicting patient survival. Methods We retrospectively reviewed the data of all patients treated for spinal metastasis between March 2003 and March 2012 in our centre. We computed the Tokuhashi and Tomita scores and compared them with documented patient survival. The 2 scores were also compared with one another. Results We identified 128 patients with spinal metastasis. The average survival of patients with predicted poor, average and good prognosis was 5, 17 and 25 months, respectively for the modified Tokuhashi score and 3, 16 and 19 months, respectively, for the Tomita score. Poor, average and good prognosis predictions differed significantly from one another for all 3 categories for the Tokuhashi score (all p &lt; 0.05). There was no significant difference in the moderate and good prognoses for the Tomita score ( p = 0.15). When comparing both scores, we obtained a weighted ? of 0.4489 (standard deviation 0.0568, 95% confidence interval 0.3376–0.5602), demonstrating moderate agreement between scores. Conclusion Both scores have merit for use in a clinical setting and can be used as tools to help determine treatment choice. The modified Tokuhashi score had better accuracy in determining actual survival.</abstract><cop>Canada</cop><pub>CMA Joule Inc</pub><pmid>24869611</pmid><doi>10.1503/cjs.012013</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Cancer
Care and treatment
Chemotherapy
Decision Support Techniques
Effectiveness
Female
Follow-Up Studies
Humans
Kaplan-Meier Estimate
Male
Medical prognosis
Metastasis
Middle Aged
Prognosis
Radiotherapy
Retrospective Studies
Severity of Illness Index
Spinal Neoplasms - mortality
Spinal Neoplasms - secondary
Spinal Neoplasms - therapy
Standard scores
Studies
Surgery
Survival analysis
Survival Rate
title A comparison of the modified Tokuhashi and Tomita scores in determining prognosis for patients afflicted with spinal metastasis
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