Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia

Schizophrenia patients exhibit increased hippocampal activity that is correlated with positive symptoms. Although the cause of this hippocampal hyperactivity has not been demonstrated, it likely involves a decrease in GABAergic signaling. Thus, we posit that restoring GABAergic function may provide...

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