NADPH oxidases in vascular pathology

Reactive oxygen species (ROS) play a critical role in vascular disease. While there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases play a central role. They are a source of "kindling radicals," which affect other enzymes, such as nitric oxide...

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Veröffentlicht in:	Antioxidants & redox signaling 2014-06, Vol.20 (17), p.2794-2814
Hauptverfasser:	Konior, Anna, Schramm, Agata, Czesnikiewicz-Guzik, Marta, Guzik, Tomasz J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis - enzymology Atherosclerosis - pathology Endothelium, Vascular - enzymology Endothelium, Vascular - pathology Forum Review Humans Muscle, Smooth, Vascular - enzymology Muscle, Smooth, Vascular - pathology NADPH Oxidases - classification NADPH Oxidases - genetics NADPH Oxidases - metabolism Oxidative Stress - genetics Protein Isoforms - genetics Protein Isoforms - metabolism Reactive Oxygen Species - metabolism Risk Factors
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