A novel in vivo model for evaluating functional restoration of a tissue-engineered salivary gland

Objectives/Hypothesis To create a novel model for development of a tissue‐engineered salivary gland from human salivary gland cells that retains progenitor cell markers useful for treatment of radiation‐induced xerostomia. Study Design A three‐dimensional (3D) hyaluronic acid (HA)‐based hydrogel sca...

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Veröffentlicht in:	The Laryngoscope 2014-02, Vol.124 (2), p.456-461
Hauptverfasser:	Pradhan-Bhatt, Swati, Harrington, Daniel A., Duncan, Randall L., Farach-Carson, Mary C., Jia, Xinqiao, Witt, Robert L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Bioartificial organ Humans hyaluronic acid receptors hyaluronic acid-based hydrogels Hydrogels Male Middle Aged progenitor cells Rats Rats, Sprague-Dawley Recovery of Function regeneration Rodents salivary gland Salivary Glands - physiology Salivary Glands - surgery Spheroids three-dimensional cell culture tissue engineering Tissue Engineering - methods
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