Roles of Vascular Endothelial Growth Factor in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal devastating neurodegenerative disorder, involving progressive degeneration of motor neurons in spinal cord, brainstem, and motor cortex. Riluzole is the only drug approved in ALS but it only confers a modest improvement in survival. In spite of a high n...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-24
Hauptverfasser:	Pronto-Laborinho, Ana Catarina, Pinto, Susana, De Carvalho, Mamede
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - drug therapy Amyotrophic Lateral Sclerosis - metabolism Amyotrophic Lateral Sclerosis - pathology Animals Axons - metabolism Axons - pathology Brain Stem - metabolism Brain Stem - pathology Cell Movement - drug effects Development and progression Diabetes Disease Models, Animal Gene expression Health aspects Humans Hypoxia Moniz, Egas Motor Cortex - metabolism Motor Cortex - pathology Mutation Neuroprotective Agents - therapeutic use Proteins Receptors, Vascular Endothelial Growth Factor - metabolism Review Riluzole - therapeutic use Rodents Spinal cord Spinal Cord - metabolism Spinal Cord - pathology Vascular endothelial growth factor Vascular Endothelial Growth Factor B
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!