Toll-Like Receptor-4 deficiency enhances repair of ultraviolet radiation induced cutaneous DNA damage by nucleotide excision repair mechanism

UVB-induced DNA damage plays a critical role in development of photoimmunosuppression. The purpose of this study was to determine whether repair of UVB-induced DNA damage is regulated by Toll-like receptor-4 (TLR4). When TLR4 gene knockout (TLR4 -/- ) and TLR4 competent (TLR4 +/+ ) mice were subject...

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Veröffentlicht in:	Journal of investigative dermatology 2013-12, Vol.134 (6), p.1710-1717
Hauptverfasser:	Ahmad, Israr, Simanyi, Eva, Guroji, Purushotham, Tamimi, Iman A, delaRosa, Hillary J, Nagar, Anusuiya, Nagar, Priyamvada, Katiyar, Santosh K, Elmets, Craig A, Yusuf, Nabiha
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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