Principles of Protein-Protein Interactions
This review examines protein complexes in the Brookhaven Protein Databank to gain a better understanding of the principles governing the interactions involved in protein-protein recognition. The factors that influence the formation of protein-protein complexes are explored in four different types of...
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| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1996-01, Vol.93 (1), p.13-20 |
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| container_title | Proceedings of the National Academy of Sciences - PNAS |
| container_volume | 93 |
| creator | Jones, Susan Thornton, Janet M. |
| description | This review examines protein complexes in the Brookhaven Protein Databank to gain a better understanding of the principles governing the interactions involved in protein-protein recognition. The factors that influence the formation of protein-protein complexes are explored in four different types of protein-protein complexes--homodimeric proteins, heterodimeric proteins, enzyme-inhibitor complexes, and antibody-protein complexes. The comparison between the complexes highlights differences that reflect their biological roles. |
| doi_str_mv | 10.1073/pnas.93.1.13 |
| format | Article |
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Thornton, Janet M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c546t-6b911244657baa7e190a2a1f5b3b1216967e1fd3698fcb2ba2ce993a2a57c8383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Amino acids</topic><topic>Animals</topic><topic>Antigen-Antibody Complex - chemistry</topic><topic>Atoms</topic><topic>Crystallography, X-Ray</topic><topic>Cytochromes</topic><topic>Datasets</topic><topic>Dimers</topic><topic>Humans</topic><topic>Hydrogen Bonding</topic><topic>Hydrogen bonds</topic><topic>Hydrophobicity</topic><topic>Macromolecular Substances</topic><topic>Molecular biology</topic><topic>Molecular weight</topic><topic>Molecules</topic><topic>Monomers</topic><topic>Protein Binding</topic><topic>Protein Conformation</topic><topic>Protein Structure, Secondary</topic><topic>Proteins</topic><topic>Proteins - chemistry</topic><topic>Review</topic><topic>Solubility</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jones, Susan</creatorcontrib><creatorcontrib>Thornton, Janet M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jones, Susan</au><au>Thornton, Janet M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Principles of Protein-Protein Interactions</atitle><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle><addtitle>Proc Natl Acad Sci U S A</addtitle><date>1996-01-09</date><risdate>1996</risdate><volume>93</volume><issue>1</issue><spage>13</spage><epage>20</epage><pages>13-20</pages><issn>0027-8424</issn><eissn>1091-6490</eissn><abstract>This review examines protein complexes in the Brookhaven Protein Databank to gain a better understanding of the principles governing the interactions involved in protein-protein recognition. 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| fulltext | fulltext |
| identifier | ISSN: 0027-8424 |
| ispartof | Proceedings of the National Academy of Sciences - PNAS, 1996-01, Vol.93 (1), p.13-20 |
| issn | 0027-8424 1091-6490 |
| language | eng |
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| source | MEDLINE; JSTOR Archive Collection A-Z Listing; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Amino acids Animals Antigen-Antibody Complex - chemistry Atoms Crystallography, X-Ray Cytochromes Datasets Dimers Humans Hydrogen Bonding Hydrogen bonds Hydrophobicity Macromolecular Substances Molecular biology Molecular weight Molecules Monomers Protein Binding Protein Conformation Protein Structure, Secondary Proteins Proteins - chemistry Review Solubility Structure-Activity Relationship |
| title | Principles of Protein-Protein Interactions |
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