The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses

The very low density lipoprotein receptor (VLDLR) is a member of the low-density lipoprotein receptor family that binds multiple ligands and plays a key role in brain development. Although the VLDLR mediates pleiotropic biological processes, only a limited amount of information is available regardin...

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Veröffentlicht in:	The Journal of immunology (1950) 2014-05, Vol.192 (10), p.4497-4509
Hauptverfasser:	Fredriksson, Karin, Mishra, Amarjit, Lam, Jonathan K, Mushaben, Elizabeth M, Cuento, Rosemarie A, Meyer, Katharine S, Yao, Xianglan, Keeran, Karen J, Nugent, Gayle Z, Qu, Xuan, Yu, Zu-Xi, Yang, Yanqin, Raghavachari, Nalini, Dagur, Pradeep K, McCoy, J Philip, Levine, Stewart J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity Animals CD11c Antigen - genetics CD11c Antigen - immunology Cell Adhesion Molecules - genetics Cell Adhesion Molecules - immunology Cytokines - genetics Cytokines - immunology Dendritic Cells - immunology Dendritic Cells - pathology Eosinophils - immunology Eosinophils - pathology Female Genome-Wide Association Study Humans Immunoglobulin E - genetics Immunoglobulin E - immunology Lectins, C-Type - genetics Lectins, C-Type - immunology Male Mice Mice, Knockout Pyroglyphidae Receptors, Cell Surface - genetics Receptors, Cell Surface - immunology Receptors, LDL - genetics Receptors, LDL - immunology Respiratory Hypersensitivity - genetics Respiratory Hypersensitivity - immunology Respiratory Hypersensitivity - pathology Th2 Cells - immunology Th2 Cells - pathology
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