Surface coatings of ZnO nanoparticles mitigate differentially a host of transcriptional, protein and signalling responses in primary human olfactory cells

Inhaled nanoparticles have been reported in some instances to translocate from the nostril to the olfactory bulb in exposed rats. In close proximity to the olfactory bulb is the olfactory mucosa, within which resides a niche of multipotent cells. Cells isolated from this area may provide a relevant...

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Veröffentlicht in:	Particle and fibre toxicology 2013-10, Vol.10 (1), p.54-54
Hauptverfasser:	Osmond-McLeod, Megan J, Osmond, Ronald I W, Oytam, Yalchin, McCall, Maxine J, Feltis, Bryce, Mackay-Sim, Alan, Wood, Stephen A, Cook, Anthony L
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Bulbs Cells Cellular Cellular signal transduction Coatings Culture Media Cytokines - metabolism Gene Expression Profiling Genetic transcription Genomics Health aspects Human Humans Kinases Medical research Metal Nanoparticles Microscopy, Electron, Transmission Nanoparticles Olfactory Mucosa - cytology Olfactory Mucosa - metabolism Oligonucleotide Array Sequence Analysis Physiological aspects Rodents Signal Transduction - drug effects Signalling Stem cells Surface Properties Transcription, Genetic - drug effects Workplaces Zinc oxide Zinc Oxide - chemistry Zinc Oxide - pharmacology Zinc oxides
Online-Zugang:	Volltext
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