Proximal Tumor Location and Fluid-fluid Levels on MRI Predict Resistance to Chemotherapy in Stage IIB Osteosarcoma

Background Primary tumor growth during neoadjuvant chemotherapy is believed to be a sign of resistance to chemotherapy (chemoresistance), and often is associated with poor histologic response, local recurrence, and poorer survival. Currently there are no proven indicators to predict poor response to...

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Veröffentlicht in:	Clinical orthopaedics and related research 2014-06, Vol.472 (6), p.1911-1920
Hauptverfasser:	Jeon, Dae-Geun, Song, Won Seok, Cho, Wan Hyeong, Kong, Chang-Bae, Cho, Sang Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antineoplastic Agents - therapeutic use Bone Neoplasms - drug therapy Bone Neoplasms - mortality Bone Neoplasms - pathology Chemotherapy, Adjuvant Child Child, Preschool Clinical Research Conservative Orthopedics Disease-Free Survival Drug Resistance, Neoplasm Female Humans Kaplan-Meier Estimate Logistic Models Magnetic Resonance Imaging Male Medicine Medicine & Public Health Middle Aged Multivariate Analysis Neoadjuvant Therapy Neoplasm Staging Odds Ratio Orthopedics Osteosarcoma - drug therapy Osteosarcoma - mortality Osteosarcoma - pathology Predictive Value of Tests Proportional Hazards Models Retrospective Studies Risk Factors Sports Medicine Surgery Surgical Orthopedics Time Factors Treatment Failure Tumor Tumor Burden Young Adult
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