DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics

De novo loss-of-function (dnLoF) mutations are found twofold more often in autism spectrum disorder (ASD) probands than their unaffected siblings. Multiple independent dnLoF mutations in the same gene implicate the gene in risk and hence provide a systematic, albeit arduous, path forward for ASD gen...

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Veröffentlicht in:	Molecular autism 2014-03, Vol.5 (1), p.22-22, Article 22
Hauptverfasser:	Liu, Li, Lei, Jing, Sanders, Stephan J, Willsey, Arthur Jeremy, Kou, Yan, Cicek, Abdullah Ercument, Klei, Lambertus, Lu, Cong, He, Xin, Li, Mingfeng, Muhle, Rebecca A, Ma'ayan, Avi, Noonan, James P, Sestan, Nenad, McFadden, Kathryn A, State, Matthew W, Buxbaum, Joseph D, Devlin, Bernie, Roeder, Kathryn
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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