Engineering aldolases as biocatalysts

•Aldolase enzymes are attractive candidates as biocatalysts.•Stability, stereoselectivity and substrate specificity of aldolases have been altered.•Aldolases with desirable activities have been produced using a variety of methods.•Combining computational with other methods produces efficient designe...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Current opinion in chemical biology 2014-04, Vol.19 (100), p.25-33
Hauptverfasser:	Windle, Claire L, Müller, Marion, Nelson, Adam, Berry, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehyde-Lyases - chemistry Aldehyde-Lyases - metabolism Biocatalysis Catalytic Domain Enzyme Stability Humans Protein Engineering Substrate Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!