A gamma‐interferon‐induced factor that binds the interferon response sequence of the MHC class I gene, H‐2Kb

Transcription of class I genes of the major histocompatibility complex (MHC) can be induced by interferons. Treatment of HeLa cells with interferon‐gamma induces a DNA‐binding factor, IBP‐1, specific for a site within the interferon response sequence (IRS) of the H‐2Kb promoter. The mol. wt of IBP‐1...

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Veröffentlicht in:	The EMBO journal 1989-04, Vol.8 (4), p.1139-1144
Hauptverfasser:	Blanar, M. A., Baldwin, A. S., Flavell, R. A., Sharp, P. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Base Sequence Binding and carrier proteins Binding Sites Biological and medical sciences Cycloheximide - pharmacology DNA - metabolism DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Fundamental and applied biological sciences. Psychology Genes, MHC Class I H-2 Antigens - genetics HeLa Cells Humans Interferon-gamma - pharmacology Kinetics Mice Mutation Proteins
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