Present and Possible Therapies for Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly population worldwide and is defined as a chronic, progressive disorder characterized by changes occurring within the macula reflective of the ageing process. At present, the prevalence of AMD is currently ris...
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Veröffentlicht in: | ISRN ophthalmology 2014-04, Vol.2014, p.608390-7 |
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description | Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly population worldwide and is defined as a chronic, progressive disorder characterized by changes occurring within the macula reflective of the ageing process. At present, the prevalence of AMD is currently rising and is estimated to increase by a third by 2020. Although our understanding of the several components underpinning the pathogenesis of this condition has increased significantly, the treatment options for this condition remain substantially limited. In this review, we outline the existing arsenal of therapies available for AMD and discuss the additional role of further novel therapies currently under investigation for this debilitating disease. |
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At present, the prevalence of AMD is currently rising and is estimated to increase by a third by 2020. Although our understanding of the several components underpinning the pathogenesis of this condition has increased significantly, the treatment options for this condition remain substantially limited. In this review, we outline the existing arsenal of therapies available for AMD and discuss the additional role of further novel therapies currently under investigation for this debilitating disease.</description><identifier>ISSN: 2090-5688</identifier><identifier>ISSN: 2090-5696</identifier><identifier>EISSN: 2090-5696</identifier><identifier>DOI: 10.1155/2014/608390</identifier><identifier>PMID: 25097787</identifier><language>eng</language><publisher>Egypt: Hindawi Publishing Corporation</publisher><subject>Review</subject><ispartof>ISRN ophthalmology, 2014-04, Vol.2014, p.608390-7</ispartof><rights>Copyright © 2014 Muhammad Khan et al.</rights><rights>Copyright © 2014 Muhammad Khan et al. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2610-b267c474dbeab2337fd9a2a73f1384a08c18580393d6400b7870cd41f6ef62213</citedby><cites>FETCH-LOGICAL-c2610-b267c474dbeab2337fd9a2a73f1384a08c18580393d6400b7870cd41f6ef62213</cites><orcidid>0000-0001-8807-2970 ; 0000-0002-6054-0952 ; 0000-0002-1430-0317</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009180/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009180/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25097787$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kakehashi, A.</contributor><contributor>Bashshur, Z.</contributor><contributor>Pierro, L.</contributor><creatorcontrib>Khan, Muhammad</creatorcontrib><creatorcontrib>Agarwal, Ketan</creatorcontrib><creatorcontrib>Loutfi, Mohamed</creatorcontrib><creatorcontrib>Kamal, Ahmed</creatorcontrib><title>Present and Possible Therapies for Age-Related Macular Degeneration</title><title>ISRN ophthalmology</title><addtitle>ISRN Ophthalmol</addtitle><description>Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly population worldwide and is defined as a chronic, progressive disorder characterized by changes occurring within the macula reflective of the ageing process. At present, the prevalence of AMD is currently rising and is estimated to increase by a third by 2020. Although our understanding of the several components underpinning the pathogenesis of this condition has increased significantly, the treatment options for this condition remain substantially limited. 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subjects | Review |
title | Present and Possible Therapies for Age-Related Macular Degeneration |
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